Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162508 | 0.81 | MAPT (0.63) | KDM4ES1PR2ALDH1A1LMNATP53 | |
| SCHEMBL5160310 | 0.79 | KDM4E (0.43) | KDM4ES1PR2ALDH1A1LMNATP53 | |
| SCHEMBL5160518 | 0.79 | ALDH1A1 (0.47) | KDM4ES1PR2ALDH1A1LMNATP53 | |
| SCHEMBL5161441 | 0.76 | MAPT (0.70) | KDM4ES1PR2ALDH1A1LMNATP53 | |
| SCHEMBL5163599 | 0.76 | KDM4E (0.40) | KDM4ES1PR2ALDH1A1LMNATP53 | |
| SCHEMBL5162492 | 0.76 | KDM4E (0.40) | KDM4ES1PR2ALDH1A1LMNATP53 | |
| SCHEMBL5162910 | 0.76 | KDM4E (0.40) | KDM4ES1PR2ALDH1A1LMNATP53 | |
| SCHEMBL5162444 | 0.76 | ALDH1A1 (0.47) | KDM4ES1PR2ALDH1A1LMNATP53 | |
| SCHEMBL5161513 | 0.74 | KDM4E (0.40) | KDM4ES1PR2ALDH1A1LMNATP53 | |
| SCHEMBL5160814 | 0.74 | MIF (0.39) | KDM4ES1PR2ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399114-B1 | AGENT CONTAINING QUINONIMINE DERIVATIVES AND USED TO COLOUR KERATIN FIBRES, AND ASSOCIATED METHOD | WELLA AG (DE) | 2007-03-28 | — | — | EP | claimed |
| US-7056349-B2 | Agent containing quinonimine derivatives and used to color keratin fibres, and associated method | WELLA AG (DE) | 2006-06-06 | — | — | US | claimed |
| EP-1399114-A1 | AGENT CONTAINING QUINONIMINE DERIVATIVES AND USED TO COLOUR KERATIN FIBRES, AND ASSOCIATED METHOD | Wella Aktiengesellschaft (DE) | 2004-03-24 | — | — | EP | claimed |
| US-20030182736-A1 | Agent containing quinonimine derivatives and used to colour keratin fibres, and associated method | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-10-02 | — | — | US | claimed |
| WO-2002102336-A1 | AGENT CONTAINING QUINONIMINE DERIVATIVES AND USED TO COLOUR KERATIN FIBRES, AND ASSOCIATED METHOD | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-27 | — | — | WO | claimed |
| EP-1399114-B1 | AGENT CONTAINING QUINONIMINE DERIVATIVES AND USED TO COLOUR KERATIN FIBRES, AND ASSOCIATED METHOD | WELLA AG (DE) | 2007-03-28 | — | — | EP | disclosed |
| US-7056349-B2 | Agent containing quinonimine derivatives and used to color keratin fibres, and associated method | WELLA AG (DE) | 2006-06-06 | — | — | US | disclosed |
| EP-1399114-A1 | AGENT CONTAINING QUINONIMINE DERIVATIVES AND USED TO COLOUR KERATIN FIBRES, AND ASSOCIATED METHOD | Wella Aktiengesellschaft (DE) | 2004-03-24 | — | — | EP | disclosed |
| US-20030182736-A1 | Agent containing quinonimine derivatives and used to colour keratin fibres, and associated method | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-10-02 | — | — | US | disclosed |
| WO-2002102336-A1 | AGENT CONTAINING QUINONIMINE DERIVATIVES AND USED TO COLOUR KERATIN FIBRES, AND ASSOCIATED METHOD | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030182736-A1 | Agent containing quinonimine derivatives and used to colour keratin fibres, and associated method | KRT18, MKI67, F12 | KDM4E 1060/4885S1PR2 4774/4885ALDH1A1 380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.