Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4409583 | 0.78 | KMT2A (0.46) | ALDH1A1L3MBTL1MAPK1HTTKMT2A | |
| SCHEMBL14920013 | 0.77 | IDO1 (0.47) | CA1CA2CA7CA9CA12 | |
| SCHEMBL944259 | 0.76 | CA1 (0.55) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1405475 | 0.75 | CA1 (0.60) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1405477 | 0.75 | CA1 (0.60) | CA1CA2CA7CA9CA12 | |
| SCHEMBL55260 | 0.75 | CA1 (0.60) | CA1CA2CA7CA9CA12 | |
| SCHEMBL11317412 | 0.75 | ACHE (0.50) | ALDH1A1L3MBTL1MAPK1KMT2AHPGD | |
| SCHEMBL1575877 | 0.73 | CA1 (0.57) | CA1CA2CA7CA9CA12 | |
| SCHEMBL13185882 | 0.71 | CA1 (0.55) | CA1CA2CA7CA9CA12 | |
| SCHEMBL3325213 | 0.71 | CA1 (0.55) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105002256-B | Combined-enzyme method, which is split, prepares the pure R- of optically-active（-）The method of tamsulosin | 杭州人可生物制品有限公司 | 2018-02-23 | — | — | CN | disclosed |
| EP-1765332-A2 | TRISUBSTITUTED NITROGEN MODULATORS OF TYROSINE PHOSPHATASES | Cengent Therapeutics, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006009876-A2 | TRISUBSTITUTED NITROGEN MODULATORS OF TYROSINE PHOSPHATASES | CENGENT THERAPEUTICS, INC. (US) | 2006-01-26 | — | — | WO | disclosed |