SCHEMBL5163702

SCHEMBL5163702

Cc1cc(Sc2cc(C)oc2C)c(C)o1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.38
MAPT P10636 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CA1 P00915 3/20 0.33
CA9 Q16790 3/20 0.33
TDP1 Q9NUW8 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
HSD17B10 Q99714 1/20 0.31
GLA P06280 1/20 0.31
CYP3A4 P08684 1/20 0.31
ALOX5 P09917 1/20 0.31
RAB9A P51151 1/20 0.31
CA12 O43570 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3508454 0.83 NQO1 (0.38) NQO1MAPTKDM4ECA1CA9
SCHEMBL4572610 0.81
SCHEMBL11621777 0.79
SCHEMBL2970154 0.79 SLC6A4 (0.50) MAPTKDM4ECA1TDP1MEN1
SCHEMBL4572609 0.75 ALDH1A1 (0.37) NQO1MAPTKDM4EMEN1KMT2A
SCHEMBL5499242 0.74 MAPT (0.41) NQO1MAPTKDM4EMEN1KMT2A
SCHEMBL8985739 0.74 USP2 (0.38) NQO1MAPTKDM4EHPGDALOX15
SCHEMBL3507263 0.72 MAPT (0.40) NQO1MAPTKDM4ECA1CA9
SCHEMBL11686616 0.72 KDM4E (0.32) NQO1MAPTKDM4EMEN1KMT2A
SCHEMBL11622877 0.72 KDM4E (0.33) NQO1MAPTKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4293579-A Flavoring with 3,5-di-(2-methylpropyl)-1,2,4-trithiolane INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-10-06 US claimed
US-4041186-A ADJUVANTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-08-09 US claimed
US-4031256-A ORGANOLEPTIC, NUTTY TASTE INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-06-21 US claimed
US-4020175-A MEAT AROMA AND FLAVOR INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-04-26 US claimed
US-3985908-A 3-Furyl sulfides and foodstuff flavor compositions comprising same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-10-12 US claimed
EP-1276391-B1 ETHYL 4-(THIOACETOXY)BUTYRATE AS A FLAVORING AGENT AND METHODS FOR PREPARING AND USING SAME BUSH BOAKE ALLEN INC (US) 2007-03-07 EP disclosed
EP-1276391-A4 ETHYL 4-(THIOACETOXY)BUTYRATE AS A FLAVORING AGENT AND METHODS FOR PREPARING AND USING SAME BUSH BOAKE ALLEN INC (US) 2005-11-09 EP disclosed
US-6899911-B2 Ethyl 4-(thioacetoxy)butyrate as a flavoring agent and methods for preparing and using same INTERNATIONAL FLAVORS & FRAGRANCES, INC. 2005-05-31 US disclosed
EP-1280419-A4 FURFURYL PROPYL DISULFIDE AS A FLAVORING AGENT AND METHODS FOR PREPARING AND USING SAME BUSH BOAKE ALLEN INC (US) 2005-01-19 EP disclosed
US-6824805-B2 ADMIXING INGESTIBLE VEHICLE (MEAT, DAIRY, AND BEVERAGE PRODUCTS) WITH ORGANOLEPTIC PURIFIED FURFURYL PROPYL DISULFIDE FORMED BY REACTING SODIUM FURFURYLTHIOLATE WITH SODIUM PROPYLTHIOSULFATE BUSH BOAKE ALLEN LTD. 2004-11-30 US disclosed
EP-1280419-A1 FURFURYL PROPYL DISULFIDE AS A FLAVORING AGENT AND METHODS FOR PREPARING AND USING SAME Bush Boake Allen Inc. (US) 2003-02-05 EP disclosed
EP-1276391-A1 ETHYL 4-(THIOACETOXY)BUTYRATE AS A FLAVORING AGENT AND METHODS FOR PREPARING AND USING SAME Bush Boake Allen Inc. (US) 2003-01-22 EP disclosed
US-4259507-A ROAST PORK FLAVOR INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-03-31 US disclosed
US-4041186-A ADJUVANTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-08-09 US disclosed
US-4031256-A ORGANOLEPTIC, NUTTY TASTE INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-06-21 US disclosed
US-4020175-A MEAT AROMA AND FLAVOR INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-04-26 US disclosed
US-4007287-A Flavoring with (allyl)(2-methyl-3-furyl) sulfide INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-02-08 US disclosed
US-3988510-A 3-Furyl sulfides and foodstuff flavor compositions comprising same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-10-26 US disclosed
US-3985908-A 3-Furyl sulfides and foodstuff flavor compositions comprising same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-10-12 US disclosed
US-3985907-A Novel 3-furyl beta oxoalkyl sulfides, processes for producing same and methods for using same for altering the organoleptic properties of foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-10-12 US disclosed