SCHEMBL5164

SCHEMBL5164

Brc1cccc(-c2ccccc2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.57
NPC1 O15118 3/20 0.57
RAB9A P51151 3/20 0.57
TSHR P16473 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
MAPK1 P28482 2/20 0.57
TP53 P04637 1/20 0.57
GABRG2 P18507 4/20 0.57
GABRB3 P28472 4/20 0.57
GABRA5 P31644 4/20 0.57
GABRA3 P34903 4/20 0.57
GABRA1 P14867 1/20 0.57
TDP1 Q9NUW8 1/20 0.53
BIRC5 O15392 1/20 0.52
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
MAOA P21397 2/20 0.50
IDO1 P14902 2/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29369904 1.00 ALDH1A1 (0.57) ALDH1A1NPC1RAB9ATSHRSMN1; SMN2
Benzene SCHEMBL28146981 1.00 ALDH1A1 (0.57) ALDH1A1NPC1RAB9ATSHRSMN1; SMN2
Water SCHEMBL28579064 0.97 NPC1 (0.55) ALDH1A1NPC1RAB9ATSHRSMN1; SMN2
SCHEMBL30433694 0.97 ALDH1A1 (0.62) ALDH1A1NPC1RAB9ATSHRSMN1; SMN2
SCHEMBL29407868 0.97 NPC1 (0.55) ALDH1A1NPC1RAB9ATSHRSMN1; SMN2
SCHEMBL18717938 0.97 NPC1 (0.55) ALDH1A1NPC1RAB9ATSHRSMN1; SMN2
SCHEMBL31063718 0.97 NPC1 (0.55) ALDH1A1NPC1RAB9ATSHRSMN1; SMN2
SCHEMBL17279673 0.97 NPC1 (0.55) ALDH1A1NPC1RAB9ATSHRSMN1; SMN2
SCHEMBL15197439 0.97 ALDH1A1 (0.62) ALDH1A1NPC1RAB9ATSHRSMN1; SMN2
SCHEMBL31177102 0.97 NPC1 (0.55) ALDH1A1NPC1RAB9ATSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2471 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118240224-A Stable high specific surface metal organic frame material, preparation method thereof and application thereof in air water collection 浙江大学杭州国际科创中心 2024-06-25 CN claimed
CN-116284026-B Water-soluble cation molecular cage and synthetic method and application thereof 天津师范大学 2024-05-14 CN claimed
CN-116284026-A Water-soluble cation molecular cage and synthetic method and application thereof 天津师范大学 2023-06-23 CN claimed
CN-112645823-B Environment-friendly fluorine-containing surfactant and preparation method thereof 绍兴市上虞区武汉理工大学高等研究院 2022-07-05 CN claimed
US-20210331991-A1 ELECTROLUMINESCENT MATERIAL WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-10-28 US claimed
CN-113149809-A 9- ([1, 1' -biphenyl ] -3-yl) -9-phenyl-2-bromofluorene and synthesis method thereof 河南省科学院化学研究所有限公司 2021-07-23 CN claimed
CN-112645823-A Environment-friendly fluorine-containing surfactant and preparation method thereof 绍兴市上虞区武汉理工大学高等研究院 2021-04-13 CN claimed
WO-2020215427-A1 ELECTROLUMINESCENT MATERIAL 武汉华星光电半导体显示技术有限公司 2020-10-29 WO claimed
CN-111574693-A PLED polymer for polar solvent processing and preparation method thereof 李建辉 2020-08-25 CN claimed
CN-106631984-B A kind of synthetic method of 9,9 '-disubstituted -3,3 '-connection carbazole 濮阳惠成电子材料股份有限公司 2019-04-16 CN claimed
CN-106631984-A Synthesis method for 9,9'-disubstituent-3,3'-dicarbazyl 濮阳惠成电子材料股份有限公司 2017-05-10 CN claimed
CN-103936551-B A kind of method preparing 3-bromo biphenyl BEIJING JIAOTONG UNIVERSITY (CN) 2015-10-28 CN claimed
CN-103145100-B A kind of decomposing ammonium chloride prepares the continuous circulation process of hydrogenchloride and ammonia YUNAN PROV. INST. OF CHEMICAL INDUSTRY (CN) 2015-09-30 CN claimed
CN-103936551-A 3-Bromobiphenyl preparation method UNIV BEIJING JIAOTONG 2014-07-23 CN claimed
CN-103145100-A Continuous loop process for preparing hydrogen chloride and ammonia gas by decomposition of ammonium chloride YUNNAN CHEMICAL RES INST 2013-06-12 CN claimed
CN-101445590-B Synthetic method of oligomeric p-phenylacetylene high polymer photovoltaic material with supply-absorb electronic units alternately connected UNIV NORTHWESTERN POLYTECHNIC 2012-01-04 CN claimed
CN-101445590-A Synthetic method of oligomeric p-phenylacetylene high polymer photovoltaic material with supply-absorb electronic units alternately connected UNIV NORTHWESTERN POLYTECHNIC (CN) 2009-06-03 CN claimed
EP-0210886-B1 TERTIARY HALOGENATED BIPHENYL ALCOHOLS THERAPEUTICALLY USEFUL IN THE TREATMENT OF ATHERIOSCLEROSIS PIERRE FABRE MEDICAMENT (FR) 1988-08-24 EP claimed
EP-4369900-B1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2026-05-20 EP disclosed
US-3939278-A Phenoxyphenyl-acetylenes and thio analogues thereof as antithrombotic agents ELI LILLY AND COMPANY (US) 1976-02-17 US disclosed