Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.55 |
| ▸ | MPI | P34949 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | XBP1 | P17861 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5160459 | 0.87 | MAPT (0.65) | ALDH1A1MAPTNPSR1MPILMNA | |
| SCHEMBL5165245 | 0.82 | ALDH1A1 (0.79) | ALDH1A1MAPTNPSR1MPILMNA | |
| SCHEMBL5164123 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPTNPSR1MPILMNA | |
| SCHEMBL5164035 | 0.80 | MAPT (0.50) | ALDH1A1MAPTNPSR1MPILMNA | |
| SCHEMBL5163599 | 0.79 | KDM4E (0.40) | ALDH1A1MAPTNPSR1MPILMNA | |
| SCHEMBL5161357 | 0.77 | MAPT (0.62) | ALDH1A1MAPTNPSR1MPILMNA | |
| SCHEMBL5165378 | 0.74 | MAPT (0.66) | ALDH1A1MAPTNPSR1MPILMNA | |
| SCHEMBL5160646 | 0.74 | MAPT (0.65) | ALDH1A1MAPTNPSR1MPILMNA | |
| SCHEMBL5160441 | 0.72 | MAPT (0.56) | ALDH1A1MAPTNPSR1MPILMNA | |
| SCHEMBL5160298 | 0.71 | MAPT (1.00) | ALDH1A1MAPTNPSR1MPILMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399114-B1 | AGENT CONTAINING QUINONIMINE DERIVATIVES AND USED TO COLOUR KERATIN FIBRES, AND ASSOCIATED METHOD | WELLA AG (DE) | 2007-03-28 | — | — | EP | claimed |