Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.64 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.64 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27476525 | 1.00 | PRSS1 (0.64) | PRSS1PRSS2PRSS3MAPTHDAC3 | |
| SCHEMBL27834764 | 1.00 | PRSS1 (0.64) | PRSS1PRSS2PRSS3MAPTHDAC3 | |
| SCHEMBL21879683 | 1.00 | PRSS1 (0.64) | PRSS1PRSS2PRSS3MAPTHDAC3 | |
| SCHEMBL5158927 | 1.00 | PRSS1 (0.64) | PRSS1PRSS2PRSS3MAPTHDAC3 | |
| SCHEMBL4896084 | 0.98 | PRSS1 (0.61) | PRSS1PRSS2PRSS3MAPTHDAC3 | |
| Adipic Acid SCHEMBL28248016 | 0.94 | PRSS1 (0.57) | PRSS1PRSS2PRSS3MAPTHDAC3 | |
| SCHEMBL7569171 | 0.94 | PRSS1 (0.57) | PRSS1PRSS2PRSS3MAPTHDAC3 | |
| SCHEMBL25297232 | 0.94 | PRSS1 (0.70) | PRSS1PRSS2PRSS3MAPTHDAC1 | |
| SCHEMBL21879662 | 0.94 | PRSS1 (0.70) | PRSS1PRSS2PRSS3MAPTHDAC1 | |
| SCHEMBL43568 | 0.94 | PRSS1 (0.70) | PRSS1PRSS2PRSS3MAPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1519977-B1 | POLYESTERCARBONATES AND METHODS OF MANUFACTURE | GEN ELECTRIC (US) | 2007-03-07 | — | — | EP | disclosed |
| EP-1519977-A1 | POLYESTERCARBONATES AND METHODS OF MANUFACTURE | GENERAL ELECTRIC COMPANY (US) | 2005-04-06 | — | — | EP | disclosed |
| US-6689862-B2 | MELT TRANSESTERIFICATION | GENERAL ELECTRIC COMPANY | 2004-02-10 | — | — | US | disclosed |
| WO-2004005368-A1 | POLYESTERCARBONATES AND METHODS OF MANUFACTURE | GENERAL ELECTRIC COMPANY (US) | 2004-01-15 | — | — | WO | disclosed |
| US-20040010112-A1 | Polycarbonateester copolymer;impact strength, radiation transparent, heat resistance, waterproofing | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2004-01-15 | — | — | US | disclosed |