Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4896084 | 0.96 | PRSS1 (0.61) | PRSS1PRSS2PRSS3KMT2AMAPT | |
| SCHEMBL21879683 | 0.94 | PRSS1 (0.64) | PRSS1PRSS2PRSS3KMT2AMAPT | |
| SCHEMBL27476525 | 0.94 | PRSS1 (0.64) | PRSS1PRSS2PRSS3KMT2AMAPT | |
| SCHEMBL5164147 | 0.94 | PRSS1 (0.64) | PRSS1PRSS2PRSS3KMT2AMAPT | |
| SCHEMBL27834764 | 0.94 | PRSS1 (0.64) | PRSS1PRSS2PRSS3KMT2AMAPT | |
| SCHEMBL5158927 | 0.94 | PRSS1 (0.64) | PRSS1PRSS2PRSS3KMT2AMAPT | |
| SCHEMBL7569171 | 0.92 | PRSS1 (0.57) | PRSS1PRSS2PRSS3KMT2AMAPT | |
| SCHEMBL2058361 | 0.92 | ALDH1A1 (0.55) | PRSS1PRSS2PRSS3KMT2AMAPT | |
| SCHEMBL28234435 | 0.90 | PRSS1 (0.55) | PRSS1PRSS2PRSS3KMT2AMAPT | |
| SCHEMBL5673051 | 0.90 | ALDH1A1 (0.53) | PRSS1PRSS2PRSS3KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408093-B | Polymer material for three dimensional printing | 金伯利-克拉克环球有限公司 | 2018-09-25 | — | — | CN | disclosed |