Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4444920 | 0.81 | NPC1 (0.46) | NPC1RAB9ALMNATSHRNFKB1 | |
| SCHEMBL26658058 | 0.80 | NPC1 (0.40) | NPC1RAB9ALMNATP53CYP3A4 | |
| SCHEMBL26658032 | 0.80 | NPC1 (0.40) | NPC1RAB9ALMNATP53CYP3A4 | |
| SCHEMBL26658047 | 0.80 | NPC1 (0.40) | NPC1RAB9ALMNATP53CYP3A4 | |
| SCHEMBL26657983 | 0.80 | NPC1 (0.40) | NPC1RAB9ALMNATP53CYP3A4 | |
| SCHEMBL26658070 | 0.80 | NPC1 (0.40) | NPC1RAB9ALMNATP53CYP3A4 | |
| SCHEMBL26657995 | 0.80 | NPC1 (0.40) | NPC1RAB9ALMNATP53CYP3A4 | |
| SCHEMBL26658001 | 0.80 | NPC1 (0.40) | NPC1RAB9ALMNATP53CYP3A4 | |
| SCHEMBL20363907 | 0.80 | NPC1 (0.47) | NPC1RAB9ALMNACYP1A2TSHR | |
| SCHEMBL31267544 | 0.80 | NPC1 (0.42) | NPC1RAB9ALMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086978-B1 | ADDITIVE-CONTAINING MOLDED RESIN AND PROCESS FOR PRODUCING THE SAME | TAKIRON CO (JP) | 2007-04-11 | — | — | EP | claimed |
| US-6569531-B1 | Adding multifunctional additive to thermoplastic polyester resin, allowing to react with molecules of resin which is in molten state, molding to produce additive-containing resin molded article | TAKIRON CO., LTD. (JP) | 2003-05-27 | — | — | US | claimed |
| EP-1086978-A1 | ADDITIVE-CONTAINING MOLDED RESIN AND PROCESS FOR PRODUCING THE SAME | Takiron Co., Ltd. (JP) | 2001-03-28 | — | — | EP | claimed |