SCHEMBL4444920

SCHEMBL4444920

CC(O)c1cc(Cc2cc(C(C)O)cc(-n3nc4ccccc4n3)c2O)c(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.46
RAB9A P51151 7/20 0.46
LMNA P02545 1/20 0.42
POLB P06746 2/20 0.41
KDM4E B2RXH2 6/20 0.35
ALDH1A1 P00352 6/20 0.34
SMN1; SMN2 Q16637 4/20 0.34
HPGD P15428 4/20 0.34
TDP1 Q9NUW8 3/20 0.34
MAPT P10636 2/20 0.34
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CASP3 P42574 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
UGT2B7 P16662 1/20 0.32
TSHR P16473 2/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20363907 0.90 NPC1 (0.47) NPC1RAB9ALMNAPOLBKDM4E
SCHEMBL22307275 0.83 NPC1 (0.41) NPC1RAB9ALMNAPOLBKDM4E
SCHEMBL14324336 0.83 IDH1 (0.44) NPC1RAB9ALMNAPOLB
SCHEMBL16135375 0.81 NPC1 (0.40) NPC1RAB9ALMNAPOLBKDM4E
SCHEMBL5164263 0.81 NPC1 (0.40) NPC1RAB9ALMNAPOLBKDM4E
SCHEMBL7566053 0.81 NPC1 (0.44) NPC1RAB9ALMNAPOLBKDM4E
SCHEMBL26658010 0.81 NPC1 (0.46) NPC1RAB9ALMNAPOLBKDM4E
SCHEMBL258759 0.80 NPC1 (0.66) NPC1RAB9ALMNAPOLBKDM4E
SCHEMBL31267541 0.80 NPC1 (0.66) NPC1RAB9ALMNAPOLBKDM4E
SCHEMBL29494818 0.80 NPC1 (0.66) NPC1RAB9ALMNAPOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1086978-B1 ADDITIVE-CONTAINING MOLDED RESIN AND PROCESS FOR PRODUCING THE SAME TAKIRON CO (JP) 2007-04-11 EP claimed
US-6569531-B1 Adding multifunctional additive to thermoplastic polyester resin, allowing to react with molecules of resin which is in molten state, molding to produce additive-containing resin molded article TAKIRON CO., LTD. (JP) 2003-05-27 US claimed
EP-1086978-A1 ADDITIVE-CONTAINING MOLDED RESIN AND PROCESS FOR PRODUCING THE SAME Takiron Co., Ltd. (JP) 2001-03-28 EP claimed
EP-1256611-B1 Aqueous dispersion and coated product JSR CORP (JP) 2009-07-29 EP disclosed
EP-1086978-B1 ADDITIVE-CONTAINING MOLDED RESIN AND PROCESS FOR PRODUCING THE SAME TAKIRON CO (JP) 2007-04-11 EP disclosed
US-6726997-B2 WWATERPROOF, HARDNESS, RATION TRANSPARENT; PROTECTIVE COATINGS JSR CORPORATION (JP) 2004-04-27 US disclosed
US-6569531-B1 Adding multifunctional additive to thermoplastic polyester resin, allowing to react with molecules of resin which is in molten state, molding to produce additive-containing resin molded article TAKIRON CO., LTD. (JP) 2003-05-27 US disclosed
US-20030073779-A1 Aqueous dispersion and coated product JSR CORPORATION (JP) 2003-04-17 US disclosed
EP-1256611-A2 Aqueous dispersion and coated product JSR Corporation (JP) 2002-11-13 EP disclosed
EP-1086978-A1 ADDITIVE-CONTAINING MOLDED RESIN AND PROCESS FOR PRODUCING THE SAME Takiron Co., Ltd. (JP) 2001-03-28 EP disclosed