Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 7/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164353 | 1.00 | PTGER3 (0.45) | PTGER3PTGER4PTGER2PTGER1KDM4E | |
| SCHEMBL5161293 | 0.84 | SQOR (0.39) | KDM4ELMNATHRATHRBMAOB | |
| SCHEMBL5163381 | 0.80 | MAOB (0.51) | LMNATHRATHRBMAOB | |
| SCHEMBL4452496 | 0.75 | MAOB (0.56) | LMNAMAOB | |
| SCHEMBL5848689 | 0.67 | KDM4E (0.66) | PTGER3PTGER4PTGER2PTGER1KDM4E | |
| SCHEMBL5848694 | 0.67 | KDM4E (0.66) | PTGER3PTGER4PTGER2PTGER1KDM4E | |
| SCHEMBL6072384 | 0.67 | PTGER4 (0.62) | PTGER3PTGER4PTGER2PTGER1KDM4E | |
| SCHEMBL6072389 | 0.67 | PTGER4 (0.62) | PTGER3PTGER4PTGER2PTGER1KDM4E | |
| SCHEMBL3114346 | 0.66 | PTGER4 (0.74) | PTGER3PTGER4PTGER2PTGER1KDM4E | |
| SCHEMBL28326121 | 0.65 | MAOB (0.51) | THRATHRBMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758850-A1 | PREPARATION AND APPLICATIONS OF POLYMER-SUPPORTED HALOGENATED BENZOQUINONES AS OXIDATIVE AGENTS | COULADOUROS, Elias, Andrea (GR) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005121077-A1 | PREPARATION AND APPLICATIONS OF POLYMER-SUPPORTED HALOGENATED BENZOQUINONES AS OXIDATIVE AGENTS | COULADOUROS ELIAS (GR) | 2005-12-22 | — | — | WO | disclosed |