Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4205690 | 1.00 | MAPT (0.40) | MAPTCYP3A4TSHRATMTDP1 | |
| SCHEMBL4200909 | 1.00 | MAPT (0.40) | MAPTCYP3A4TSHRATMTDP1 | |
| SCHEMBL4201006 | 0.90 | MGAM (0.39) | MAPTCYP3A4TSHRTDP1KMT2A | |
| SCHEMBL4199062 | 0.90 | MGAM (0.39) | MAPTCYP3A4TSHRTDP1KMT2A | |
| SCHEMBL9180688 | 0.84 | MGAM (0.43) | MAPTCYP3A4TSHRATMTDP1 | |
| SCHEMBL1765985 | 0.84 | MGAM (0.43) | MAPTCYP3A4TSHRATMTDP1 | |
| SCHEMBL22462113 | 0.84 | GPR84 (0.50) | MAPTCYP3A4TSHRATMTDP1 | |
| SCHEMBL3676004 | 0.84 | GPR84 (0.50) | MAPTCYP3A4TSHRATMTDP1 | |
| SCHEMBL3676008 | 0.84 | GPR84 (0.50) | MAPTCYP3A4TSHRATMTDP1 | |
| SCHEMBL4203015 | 0.82 | MGAM (0.41) | CYP3A4TSHRTDP1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768952-A2 | PREPARATION OF BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | Warner-Lambert Company LLC (US) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006008612-A2 | PREPARATION OF BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | WARNER-LAMBERT COMPANY LLC (US) | 2006-01-26 | — | — | WO | disclosed |