SCHEMBL516478

SCHEMBL516478

FC(F)(F)C(F)(F)C(F)(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
ALDH1A1 P00352 2/20 0.52
PTPN1 P18031 2/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA5A P35218 1/20 0.39
CA9 Q16790 1/20 0.39
KCNN4 O15554 4/20 0.39
KIF11 P52732 1/20 0.39
MAPK1 P28482 1/20 0.35
NR1H2 P55055 3/20 0.34
NR1H3 Q13133 3/20 0.34
PGK1 P00558 1/20 0.33
PGK2 P07205 1/20 0.33
PTPN5 P54829 1/20 0.32
TRPV6 Q9H1D0 1/20 0.32
CYP1A2 P05177 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8582066 0.82 TSHR (0.58) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL6546858 0.82 SRD5A2 (0.52) TSHRPTPN1KIF11
SCHEMBL11696796 0.78 TSHR (0.52) TSHRALDH1A1PTPN1CA1CA2
Benzenethiol SCHEMBL8459810 0.77 TSHR (0.37) TSHRALDH1A1PTPN1MAPK1NR1H3
SCHEMBL3390346 0.76 TSHR (0.50) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL28423412 0.76 KCNN4 (0.38) CA1CA2CA9KCNN4MAPK1
SCHEMBL28845351 0.76 TSHR (0.50) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL4812169 0.76 TSHR (0.50) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL9800786 0.74 TSHR (0.48) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL15320774 0.74 TSHR (0.48) TSHRALDH1A1PTPN1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 461 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4466319-A1 HIGH PERFORMANCE THERMOSET RESINS FOR 3D PRINTING Noga 3D Innovations Ltd (IL) 2024-11-27 EP claimed
CN-118574903-A High performance thermosetting resins for 3D printing 诺佳3D创新有限公司 2024-08-30 CN claimed
WO-2023139579-A1 HIGH PERFORMANCE THERMOSET RESINS FOR 3D PRINTING NOGA 3D INNOVATIONS LTD (IL) 2023-07-27 WO claimed
EP-3344676-B1 CYANATE ESTER DUAL CURE RESINS FOR ADDITIVE MANUFACTURING CARBON INC (US) 2023-04-12 EP claimed
CN-111019346-B Flame-retardant high-heat-resistance resin composition, copper-clad plate and preparation method thereof 艾蒙特成都新材料科技有限公司 2022-08-12 CN claimed
CN-114678657-A Preparation method of battery diaphragm, secondary battery, battery module, battery pack and electric device 宁德时代新能源科技股份有限公司 2022-06-28 CN claimed
EP-3938478-A1 USE OF OILS COMPRISING NON-NEUROTOXIC ANTI-WEAR ADDITIVES NYCO (FR) 2022-01-19 EP claimed
WO-2021233946-A1 USE OF OILS COMPRISING NON-NEUROTOXIC ANTI-WEAR ADDITIVES NYCO (FR) 2021-11-25 WO claimed
CN-108350145-B Cyanate ester dual cure resin for additive manufacturing 卡本有限公司 2021-06-22 CN claimed
CN-106795285-B Polyimide solution, heat-resistant nonwoven fabric, and method for producing same 东丽株式会社 2020-06-05 CN claimed
EP-0446947-A2 Gas separating asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1991-09-18 EP claimed
US-4965339-A CYCLIZATION OF A POLYAMIC ACID HAVING PERFLUOROALKYL GROUPS IN A SOLVENT IN THE PRSENCE OF A LOWER FATTY MONCARBOXYLIC ACID ANHYDRIDE AND A TERTIARY AMINE; COATINGS; FILMS CENTRAL GLASS COMPANY, LIMITED (JP) 1990-10-23 US claimed
EP-0388979-A2 Derivative compound of 1,3- or 1,4-bis(hexafluoroisopropyl) benzene, or 2,2-bisphenylhexafluoropropane, ink-repellent agent containing such derivative compound, head for ink jet recording treated with such ink-repellent agent and ink jet recording device equipped with such head CANON KABUSHIKI KAISHA (JP) 1990-09-26 EP claimed
EP-0192767-B1 DERIVATIVES OF DIPHENYLHEXAFLUOROPROPANE Hughes Aircraft Company (US) 1990-05-16 EP claimed
EP-0192766-B1 ETHYNYLPHENOXY AND ETHYNYLTHIOPHENOXY DERIVATIVES OF DIPHENYLHEXAFLUOROPROPANE Hughes Aircraft Company (US) 1988-09-21 EP claimed
US-4708991-A Polymers of ethynylthiophenoxy derivatives of diphenylhexafluoropropane HUGHES AIRCRAFT COMPANY (US) 1987-11-24 US claimed
US-4695655-A Ethynylthiophenoxy derivatives of diphenylhexafluoropropane HUGHES AIRCRAFT COMPANY (US) 1987-09-22 US claimed
US-4649207-A Derivatives of diphenylhexafluoropropane HUGHES AIRCRAFT COMPANY (US) 1987-03-10 US claimed
EP-0192767-A1 DERIVATIVES OF DIPHENYLHEXAFLUOROPROPANE. HUGHES AIRCRAFT CO (US) 1986-09-03 EP claimed
WO-1986001511-A1 DERIVATIVES OF DIPHENYLHEXAFLUOROPROPANE HUGHES AIRCRAFT COMPANY (US) 1986-03-13 WO claimed