Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1421315 | 1.00 | TSHR (0.48) | TSHRALDH1A1PTPN1LMNACA1 | |
| SCHEMBL10453463 | 1.00 | TSHR (0.48) | TSHRALDH1A1PTPN1LMNACA1 | |
| SCHEMBL15320774 | 1.00 | TSHR (0.48) | TSHRALDH1A1PTPN1LMNACA1 | |
| SCHEMBL1421122 | 1.00 | TSHR (0.48) | TSHRALDH1A1PTPN1LMNACA1 | |
| SCHEMBL3390346 | 0.97 | TSHR (0.50) | TSHRALDH1A1PTPN1LMNACA1 | |
| SCHEMBL30619668 | 0.92 | TSHR (0.55) | TSHRALDH1A1PTPN1CA1CA2 | |
| Dimethylamine SCHEMBL4059229 | 0.91 | KCNN4 (0.41) | TSHRALDH1A1PTPN1LMNACA1 | |
| SCHEMBL11696796 | 0.90 | TSHR (0.52) | TSHRALDH1A1PTPN1CA1CA2 | |
| SCHEMBL673282 | 0.87 | LMNA (0.43) | LMNACA1CA2THRBNR1H2 | |
| SCHEMBL1421311 | 0.87 | KIF11 (0.56) | TSHRALDH1A1PTPN1KIF11MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009039181-A2 | SULFONAMIDE-BASED ORGANOCATALYSTS AND METHOD FOR THEIR USE | STATE OF OREGON ACTING BY & THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OR. STATE UNIV. (US) | 2009-03-26 | — | — | WO | disclosed |
| EP-0245679-B1 | DEHALOGENATION PROCESS | ETHYL CORPORATION (US) | 1991-03-13 | — | — | EP | disclosed |
| US-4814497-A | Dehalogenation process | ETHYL CORPORATION (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0245679-A2 | Dehalogenation process | ETHYL CORPORATION (US) | 1987-11-19 | — | — | EP | disclosed |
| EP-0155093-B1 | METHOD FOR PRODUCTION OF FLUORINE-CONTAINING AROMATIC DERIVATIVE | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1987-10-21 | — | — | EP | disclosed |
| US-4631151-A | REACTING DI(HALOACYL)PEROXIDE WITH AROMATIC HYDROCARBON | NIPPON OIL & FARS CO., LTD. (JP) | 1986-12-23 | — | — | US | disclosed |
| EP-0155093-A2 | Method for production of fluorine-containing aromatic derivative | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1985-09-18 | — | — | EP | disclosed |
| US-4347376-A | Method of making and polymerizing perfluoroalkylene acetylene compounds | FLUORCHEM INC. (US) | 1982-08-31 | — | — | US | disclosed |