Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 4/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.53 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.53 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 14/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 14/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3856977 | 0.94 | ITGB1 (0.55) | ITGB1ITGA4ITGB7ITGA5 | |
| SCHEMBL3848928 | 0.90 | ITGB1 (0.57) | ITGB1ITGA4ITGB7ITGA5HCRTR1 | |
| SCHEMBL3852834 | 0.86 | ITGB1 (0.46) | ITGB1ITGA4ITGB7ITGA5 | |
| SCHEMBL3852610 | 0.84 | ITGA4 (0.61) | ITGB1ITGA4ITGB7ITGA5HCRTR1 | |
| SCHEMBL3848324 | 0.83 | ITGB1 (0.57) | ITGB1ITGA4ITGB7ITGA5HCRTR1 | |
| SCHEMBL3855807 | 0.83 | ITGB1 (0.56) | ITGB1ITGA4ITGB7ITGA5ALDH1A1 | |
| SCHEMBL3851029 | 0.82 | ITGB1 (0.59) | ITGB1ITGA4ITGB7ITGA5HCRTR1 | |
| SCHEMBL3851032 | 0.82 | ITGB1 (0.59) | ITGB1ITGA4ITGB7ITGA5HCRTR1 | |
| SCHEMBL7326216 | 0.82 | ITGB1 (0.49) | ITGB1ITGA4ITGB7ITGA5 | |
| SCHEMBL3850912 | 0.82 | ITGB1 (0.56) | ITGB1ITGA4ITGB7ITGA5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763361-A2 | STEROID SPARING AGENTS AND THEIR USE | Elan Pharmaceuticals, Inc. (US) | 2007-03-21 | — | — | EP | disclosed |
| WO-2005097162-A2 | STEROID SPARING AGENTS AND THEIR USE | ELAN PHARMACEUTICALS, INC. (US) | 2005-10-20 | — | — | WO | disclosed |