Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3039851 | 0.80 | CHRM3 (0.44) | NPC1ALDH1A1KMT2AKDM4ENPSR1 | |
| SCHEMBL3150975 | 0.80 | NPC1 (0.56) | NPC1GAAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL3041879 | 0.79 | CHRM3 (0.42) | NPC1GAAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL1683038 | 0.79 | TSHR (0.44) | NPC1GAAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL1136291 | 0.79 | GAA (0.31) | GAA | |
| SCHEMBL4975597 | 0.78 | CHRM3 (0.34) | KMT2ARAB9AMAPTMEN1LMNA | |
| SCHEMBL2843544 | 0.78 | CHRM3 (0.46) | NPC1ALDH1A1KDM4ENPSR1RAB9A | |
| SCHEMBL4835379 | 0.78 | CHRM3 (0.47) | — | |
| SCHEMBL4648738 | 0.78 | LMNA (0.40) | NPC1SMN1; SMN2KMT2ARAB9AMAPT | |
| SCHEMBL1396811 | 0.78 | KDM4E (0.36) | GAAALDH1A1SMN1; SMN2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761498-A1 | 1-METHYL-3-DIFLUOROMETHYL-PYRAZOL-4-CARBONIC ACID-(ORTHO-PHENYL)-ANILIDES, AND USE THEREOF AS A FUNGICIDE | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2005123690-A1 | 1-METHYL-3-DIFLUOROMETHYL-PYRAZOL-4-CARBONIC ACID-(ORTHO-PHENYL)-ANILIDES, AND USE THEREOF AS A FUNGICIDE | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-29 | — | — | WO | disclosed |