SCHEMBL516599

SCHEMBL516599

O=S(=O)(Cl)c1cnc(Cl)c(Br)c1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 12/20 0.57
GAA P10253 1/20 0.57
MAPT P10636 1/20 0.57
LMNA P02545 1/20 0.54
HTT P42858 3/20 0.51
KMT2A Q03164 2/20 0.51
JAK2 O60674 1/20 0.47
PKM P14618 1/20 0.47
MCOLN3 Q8TDD5 1/20 0.47
NPSR1 Q6W5P4 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
S100A9 P06702 1/20 0.42
CHRNB2 P17787 1/20 0.38
CHRNA4 P43681 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15067048 0.87 ALDH1A1 (0.48) ALDH1A1GAAMAPTLMNAHTT
SCHEMBL517787 0.84 ALDH1A1 (0.57) ALDH1A1GAAMAPTLMNAHTT
SCHEMBL2172819 0.82 ALDH1A1 (0.56) ALDH1A1GAAMAPTLMNAHTT
SCHEMBL2650456 0.82 ALDH1A1 (0.59) ALDH1A1GAAMAPTLMNAHTT
Hydrochloric Acid SCHEMBL27600574 0.81 ALDH1A1 (0.58) ALDH1A1GAAMAPTLMNAHTT
SCHEMBL2174000 0.79 ALDH1A1 (0.57) ALDH1A1GAAMAPTLMNAHTT
SCHEMBL31018073 0.79 ALDH1A1 (0.56) ALDH1A1GAAMAPTLMNAHTT
SCHEMBL958949 0.79 ALDH1A1 (0.56) ALDH1A1GAAMAPTLMNAHTT
SCHEMBL19748008 0.78 ALDH1A1 (0.39) ALDH1A1GAAMAPTLMNAHTT
SCHEMBL21633518 0.78 ALDH1A1 (0.37) ALDH1A1GAAMAPTLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 485 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577208-B2 TEAD inhibitors and uses thereof EHE Foundation (US) 2026-03-17 US disclosed
US-20260022096-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS GENECODE (EE) 2026-01-22 US disclosed
EP-4682148-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2026-01-21 EP disclosed
EP-4134364-B1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RES INC (US) 2025-07-30 EP disclosed
EP-4561994-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS Genecode (EE) 2025-06-04 EP disclosed
CN-120035580-A Novel piperazinyl sulfonamides and their use as neuroprotective and/or neurorestorative agents 基因密码公司 2025-05-23 CN disclosed
US-20250161318-A1 SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT ABBVIE INC (US) 2025-05-22 US disclosed
CN-119954725-A TEAD inhibitors and uses thereof 医肯纳肿瘤学公司 2025-05-09 CN disclosed
EP-4549438-A1 FIVE-MEMBERED AND SIX-MEMBERED NITROGEN-CONTAINING COMPOUND, AND INTERMEDIATE, PREPARATION METHOD AND USE THEREOF Hangzhou Synrx Therapeutics Biomedical Technology Co., Ltd. (CN) 2025-05-07 EP disclosed
CN-119948015-A Novel sulfonamides and their use as neuroprotective and/or nerve repair agents 基因密码公司 2025-05-06 CN disclosed
US-20030114500-A1 Nitrogen heterocycle inhibitors of aspartyl protease ENANTA PHARMACEUTICALS, INC. 2003-06-19 US disclosed
WO-2003048122-A2 INHIBITORS OF CYTOSOLIC PHOSPHOLIPASE A2 WYETH (US) 2003-06-12 WO disclosed
WO-2003035613-A2 NITROGEN HETEROCYCLE INHIBITORS OF ASPARTYL PROTEASE ENANTA PHARMACEUTICALS, INC. (US) 2003-05-01 WO disclosed
WO-2003022852-A2 FURO-AND THIENOPYRIMIDINE DERIVATIVES AS ANGIOGENESIS INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2003-03-20 WO disclosed
EP-1285658-A2 Treatments for female sexual dysfunction Pfizer Productors Inc. (US) 2003-02-26 EP disclosed
US-6458951-B2 FOR TREATMENT OF MALE ERECTILE DYSFUNCTION, FEMALE SEXUAL DYSFUNCTION PFIZER INC 2002-10-01 US disclosed
US-20010039271-A1 Pyrazolopyrimidinone cGMP PDE5 inhibitors for the treatment of sexual dysfunction BUNNAGE MARK EDWARD (GB) 2001-11-08 US disclosed
US-6251904-B1 Pyrazolopyrimidinone cGMP PDE5 inhibitors for the treatment of sexual dysfunction PFIZER INC. 2001-06-26 US disclosed
EP-1073658-A1 PYRAZOLOPYRIMIDINONE CGMP PDE5 INHIBITORS FOR THE TREATMENT OF SEXUAL DYSFUNCTION PFIZER INC. (US) 2001-02-07 EP disclosed
WO-1999054333-A1 PYRAZOLOPYRIMIDINONE CGMP PDE5 INHIBITORS FOR THE TREATMENT OF SEXUAL DYSFUNCTION PFIZER INC. (US) 1999-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030114500-A1 Nitrogen heterocycle inhibitors of aspartyl protease DNPEP, PREP, PEPD ALDH1A1 2133/4885GAA 193/4885MAPT 863/4885
US-20010039271-A1 Pyrazolopyrimidinone cGMP PDE5 inhibitors for the treatment of sexual dysfunction PDE5A, PDE3A, PDE3B ALDH1A1 254/4885GAA 3394/4885MAPT 4805/4885
US-20260022096-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS CNR1, CDR2, SMN1; SMN2 ALDH1A1 1383/4885GAA 2022/4885MAPT 2123/4885
US-20250161318-A1 SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT BCL2, BAX, BCL2L1 ALDH1A1 4457/4885GAA 3263/4885MAPT 3062/4885
US-12577208-B2 TEAD inhibitors and uses thereof BRCA1, BRAF, MEN1 ALDH1A1 618/4885GAA 4520/4885MAPT 1079/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.