Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 0.61 |
| ▸ | RAMP1 | O60894 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 14/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3518901 | 0.91 | CALCRL (0.64) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL5259365 | 0.88 | CALCRL (0.57) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL13313656 | 0.87 | CALCRL (0.69) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL13313720 | 0.86 | CALCRL (0.61) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL14540092 | 0.86 | CALCRL (0.67) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL3520211 | 0.84 | CALCRL (0.85) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL3520215 | 0.84 | CALCRL (0.85) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL13313664 | 0.84 | CALCRL (0.66) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL13313703 | 0.84 | CALCRL (0.57) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL13313692 | 0.84 | CALCRL (0.60) | CALCRLRAMP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1770091-A1 | CGRP-antagonists, process for their preparation as well as their use as medicaments | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2007-04-04 | — | — | EP | disclosed |