Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 19/20 | 0.57 |
| ▸ | RAMP1 | O60894 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231762 | 0.91 | CALCRL (0.58) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL4717049 | 0.91 | CALCRL (0.70) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL4923201 | 0.91 | CALCRL (0.61) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL13331923 | 0.89 | CALCRL (0.64) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL4716849 | 0.89 | CALCRL (0.74) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL4799753 | 0.88 | CALCRL (0.60) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL5166166 | 0.88 | CALCRL (0.61) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL6220762 | 0.88 | CALCRL (0.63) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL4723229 | 0.88 | CALCRL (0.63) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL14017214 | 0.86 | CALCRL (0.61) | CALCRLRAMP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833483-A1 | USE OF SELECTED CGRP ANTAGONISTS FOR CONTROLLING MENOPAUSAL HOT FLASHES | Boehringer Ingelheim International GmbH (DE) | 2007-09-19 | — | — | EP | claimed |
| WO-2006072415-A1 | USE OF SELECTED CGRP ANTAGONISTS FOR CONTROLLING MENOPAUSAL HOT FLASHES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-07-13 | — | — | WO | claimed |