SCHEMBL5166192

SCHEMBL5166192

CCCOC(=O)c1cccc(C(=O)OC)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.66
ALDH1A1 P00352 4/20 0.61
KDM4E B2RXH2 2/20 0.56
POLB P06746 1/20 0.56
TSHR P16473 3/20 0.54
ESR1 P03372 1/20 0.54
CHRM1 P11229 1/20 0.54
SLC6A2 P23975 1/20 0.54
KDR P35968 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
LOXL2 Q9Y4K0 1/20 0.54
CYP4F2 P78329 1/20 0.53
CYP4A11 Q02928 1/20 0.53
HPGD P15428 3/20 0.51
SMN1; SMN2 Q16637 4/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
RAB9A P51151 2/20 0.49
NPC1 O15118 1/20 0.49
CYP1A2 P05177 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL111664 0.93 LMNA (0.75) LMNAALDH1A1KDM4EPOLBTSHR
SCHEMBL6057190 0.90 HPGD (0.60) LMNAALDH1A1KDM4ETSHRESR1
SCHEMBL18459949 0.89 LMNA (0.58) LMNAALDH1A1KDM4EPOLBTSHR
SCHEMBL27917952 0.89 LMNA (0.57) LMNAALDH1A1TSHRESR1TDP1
SCHEMBL5165716 0.88 LMNA (0.68) LMNAALDH1A1KDM4EPOLBTSHR
SCHEMBL28111428 0.87 LMNA (0.59) LMNAALDH1A1TSHRESR1TDP1
SCHEMBL28201124 0.87 LMNA (0.59) LMNAALDH1A1TSHRESR1TDP1
SCHEMBL1531494 0.86 LMNA (0.71) LMNAALDH1A1KDM4EPOLBTSHR
SCHEMBL27286509 0.86 CYP4F2 (0.61) LMNAALDH1A1KDM4EPOLBTSHR
SCHEMBL6057202 0.86 LMNA (0.66) LMNAALDH1A1TSHRESR1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106540512-A The absorbent of sulfide in a kind of selectively removing natural gas 中国石油化工股份有限公司 2017-03-29 CN claimed
CN-105957983-A ELECTROCHEMICAL DEVICES FOR USE IN EXTREME CONDITIONS 普拉德研究及开发股份有限公司 2016-09-21 CN claimed
CN-101056628-A Ester derivatives and medicinal use thereof JAPAN TOBACCO INC (JP) 2007-10-17 CN claimed
WO-2019216200-A1 COLOR CONVERSION COMPOSITION, COLOR CONVERSION SHEET, LIGHT SOURCE UNIT, DISPLAY AND LIGHTING DEVICE 東レ株式会社 (JP) 2019-11-14 WO disclosed
CN-106540512-A The absorbent of sulfide in a kind of selectively removing natural gas 中国石油化工股份有限公司 2017-03-29 CN disclosed
CN-106398905-A Application of hydroxyl substituent of 2-amino-2-methyl propane in amino acid transparent soap 佛山市芊茹化妆品有限公司 2017-02-15 CN disclosed
CN-104918907-A Quarternary ammonium perfluoroalkoxy salts for preparation of perfluoropolyethers DU PONT 2015-09-16 CN disclosed
EP-1249471-B1 Polypropylene-based resins and polypropylene-based resin compositions PRIME POLYMER CO LTD (JP) 2013-06-26 EP disclosed
CN-102834961-A Electrochemical device for use under extreme conditions SCHLUMBERGER CA LTD 2012-12-19 CN disclosed
CN-101056628-B Ester derivatives and medicinal use thereof JAPAN TOBACCO INC 2011-05-25 CN disclosed
CN-101056628-A Ester derivatives and medicinal use thereof JAPAN TOBACCO INC (JP) 2007-10-17 CN disclosed
EP-0284005-B1 METHOD OF PRODUCTION OF POLYOLEFINS IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1991-12-18 EP disclosed
EP-0455813-A1 FLEXIBLE POLYPROPYLENE RESIN, PROPYLENE ELASTOMER COMPOSITION, AND PRODUCTION OF OLEFIN POLYMER IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1991-11-13 EP disclosed
EP-0206172-B1 METHOD FOR PRODUCING POLYOLEFINS IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1991-07-24 EP disclosed
EP-0257131-B1 METHOD FOR PRODUCING BUTENE-1 POLYMER IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1991-05-29 EP disclosed
EP-0419874-A2 Composition of polybutene-1 and process for preparing same IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) 1991-04-03 EP disclosed
US-4981930-A POLYMERIZATION CATALYSTS IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) 1991-01-01 US disclosed
EP-0284005-A2 Method of production of polyolefins IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1988-09-28 EP disclosed
EP-0257131-A2 Method for producing butene-1 polymer IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1988-03-02 EP disclosed
EP-0206172-A1 Method for producing polyolefins IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1986-12-30 EP disclosed