Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6110855 | 0.90 | CETP (0.52) | CETPNR1I2 | |
| SCHEMBL531459 | 0.85 | CETP (0.58) | CETPNR1I2 | |
| SCHEMBL4011739 | 0.85 | CETP (0.67) | CETPNR1I2 | |
| Ammonia Solution, Strong SCHEMBL5992875 | 0.84 | CETP (0.57) | CETPNR1I2 | |
| SCHEMBL4009039 | 0.83 | CETP (0.68) | CETPNR1I2 | |
| SCHEMBL133988 | 0.82 | CETP (0.60) | CETPNR1I2 | |
| SCHEMBL17965460 | 0.82 | CETP (0.60) | CETPNR1I2 | |
| SCHEMBL13413626 | 0.82 | CETP (0.59) | CETPNR1I2 | |
| SCHEMBL5165509 | 0.82 | CETP (0.54) | CETPNR1I2 | |
| SCHEMBL3305177 | 0.81 | CETP (0.68) | CETPNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765793-A1 | CETP INHIBITORS | Merck and Co., Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| US-20060040999-A1 | CETP inhibitors | MERCK SHARP & DOHME LLC | 2006-02-23 | — | — | US | disclosed |
| WO-2006014357-A1 | CETP INHIBITORS | MERCK & CO., INC. (US) | 2006-02-09 | — | — | WO | disclosed |
| WO-2006014413-A1 | CETP INHIBITORS | MERCK & CO., INC. (US) | 2006-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040999-A1 | CETP inhibitors | CETP, APOB, MTTP | CETP 1/4885NR1I2 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.