SCHEMBL5166722

SCHEMBL5166722

CC1CCC(N(C)C)CC1.CN(C)C1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 6/20 0.41
ADH1C P00326 4/20 0.41
PHGDH O43175 2/20 0.37
FAAH O00519 1/20 0.37
MGLL Q99685 1/20 0.37
EPHX1 P07099 1/20 0.35
ADH4 P08319 1/20 0.33
HRH3 Q9Y5N1 2/20 0.32
HRH4 Q9H3N8 1/20 0.32
ADH1B P00325 1/20 0.32
ACHE P22303 1/20 0.32
RECQL P46063 1/20 0.31
KMT2A Q03164 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19068074 0.92 ADH1A (0.42) ADH1AADH1CPHGDHFAAHMGLL
SCHEMBL21091459 0.89 ADH1A (0.39) ADH1AADH1CPHGDHFAAHMGLL
SCHEMBL20779789 0.89 ADH1A (0.39) ADH1AADH1CPHGDHFAAHMGLL
SCHEMBL738017 0.89 TDP1 (0.35)
SCHEMBL13448639 0.89 TDP1 (0.35)
SCHEMBL738490 0.89 TDP1 (0.35)
SCHEMBL13356252 0.86 ADH1A (0.50) ADH1AADH1CPHGDHFAAHMGLL
SCHEMBL1674941 0.86 ADH1A (0.50) ADH1AADH1CPHGDHFAAHMGLL
SCHEMBL20733112 0.86 ADH1A (0.50) ADH1AADH1CPHGDHFAAHMGLL
SCHEMBL283931 0.86 ADH1A (0.50) ADH1AADH1CPHGDHFAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1595910-B1 Derivatised, permanently quaternised nitrogen atoms bearing, linear or branched aminofunctional organopolysiloxanes SCHILL & SEILACHER STRUKTOL AG (DE) 2007-05-30 EP disclosed
EP-1561770-B1 Branched Polyorganosiloxane with quaternary Ammoniumgroups SCHILL & SEILACHER STRUKTOL AG (DE) 2007-04-04 EP disclosed
EP-1595910-A1 Derivatised, permanently quaternised nitrogen atoms bearing, linear or branched aminofunctional organopolysiloxanes Schill + Seilacher "Struktol" Aktiengesellschaft (DE) 2005-11-16 EP disclosed
EP-1561770-A1 Branched Polyorganosiloxane with quaternary Ammoniumgroups Schill + Seilacher "Struktol" Aktiengesellschaft (DE) 2005-08-10 EP disclosed