Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29362497 | 0.81 | MGAM (0.71) | MGAMNPSR1CYP1A2CFTRALDH1A1 | |
| SCHEMBL28879835 | 0.81 | MGAM (0.61) | MGAMNPSR1CYP1A2CFTRALDH1A1 | |
| SCHEMBL5674933 | 0.81 | MGAM (0.61) | MGAMNPSR1CYP1A2CFTRALDH1A1 | |
| SCHEMBL23372 | 0.81 | MGAM (0.71) | MGAMNPSR1CYP1A2CFTRALDH1A1 | |
| SCHEMBL27583240 | 0.80 | MGAM (0.69) | MGAMNPSR1CYP1A2CFTRALDH1A1 | |
| Fluoride SCHEMBL28234122 | 0.80 | MGAM (0.69) | MGAMNPSR1CYP1A2CFTRALDH1A1 | |
| Hydrochloric Acid SCHEMBL5311903 | 0.80 | MGAM (0.69) | MGAMNPSR1CYP1A2CFTRALDH1A1 | |
| Hydrochloric Acid SCHEMBL28129921 | 0.80 | MGAM (0.69) | MGAMNPSR1CYP1A2CFTRALDH1A1 | |
| Hydrochloric Acid SCHEMBL28841803 | 0.80 | MGAM (0.69) | MGAMNPSR1CYP1A2CFTRALDH1A1 | |
| SCHEMBL6604149 | 0.79 | MGAM (0.57) | MGAMNPSR1CYP1A2CFTRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605474-A | Microbicidal quinoline dihydro- (thiazine) oxazine derivatives | 先正达农作物保护股份公司（CH） | 2023-01-13 | — | — | CN | disclosed |
| EP-1224172-B1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | ACTIVE BIOTECH AB (SE) | 2007-04-04 | — | — | EP | disclosed |
| CN-1161336-C | Quinoline carboxamides as antiviral agents | �������Ŷ���Լ��������˾ | 2004-08-11 | — | — | CN | disclosed |
| CN-1333753-A | Quinoline carboxamides as antiviral agents | UPJOHN CO (US) | 2002-01-30 | — | — | CN | disclosed |