SCHEMBL5166784

SCHEMBL5166784

O=c1c2ccccc2cnn1Br

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.56
RAB9A P51151 8/20 0.56
SMN1; SMN2 Q16637 6/20 0.56
LMNA P02545 2/20 0.56
KMT2A Q03164 2/20 0.56
MEN1 O00255 1/20 0.56
GLA P06280 1/20 0.56
NFKB1 P19838 1/20 0.56
NFKB2 Q00653 1/20 0.56
RELA Q04206 1/20 0.56
ALDH1A1 P00352 4/20 0.51
POLB P06746 2/20 0.51
KDM4E B2RXH2 3/20 0.49
PLA2G10 O15496 1/20 0.47
HSD17B10 Q99714 2/20 0.46
TP53 P04637 1/20 0.46
PAX8 Q06710 1/20 0.46
MITF O75030 1/20 0.46
PKM P14618 1/20 0.46
CA12 O43570 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10622783 0.90 NPC1 (0.48) NPC1RAB9ASMN1; SMN2LMNAKMT2A
SCHEMBL17977061 0.76 NPC1 (0.51) NPC1RAB9ASMN1; SMN2LMNAKMT2A
SCHEMBL29774954 0.76 NPC1 (0.51) NPC1RAB9ASMN1; SMN2LMNAKMT2A
SCHEMBL29509350 0.76 NPC1 (0.51) NPC1RAB9ASMN1; SMN2LMNAKMT2A
SCHEMBL7764110 0.76 NPC1 (0.51) NPC1RAB9ASMN1; SMN2LMNAKMT2A
SCHEMBL332668 0.76 NPC1 (0.51) NPC1RAB9ASMN1; SMN2LMNAKMT2A
SCHEMBL14125604 0.76 NPC1 (0.51) NPC1RAB9ASMN1; SMN2LMNAKMT2A
SCHEMBL5167623 0.76 NPC1 (0.56) NPC1RAB9ASMN1; SMN2LMNAKMT2A
SCHEMBL11012126 0.76 NPC1 (0.51) NPC1RAB9ASMN1; SMN2LMNAKMT2A
SCHEMBL7889097 0.76 NPC1 (0.51) NPC1RAB9ASMN1; SMN2LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4212937-A NITROGEN-CONTAINING HETEROCYCLIC BASE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-07-15 US claimed
EP-1099977-B1 Preparation method of photothermographic material KONICA CORP (JP) 2007-04-11 EP disclosed
EP-1035430-B1 Silver halide photographic material KONISHIROKU PHOTO IND (JP) 2005-01-05 EP disclosed
US-6828086-B2 For use in imaging material KONICA CORPORATION (JP) 2004-12-07 US disclosed
EP-1033618-B1 Thermally developable photosensitive material KONISHIROKU PHOTO IND (JP) 2004-11-03 EP disclosed
US-6677113-B2 INFRARED-SENSITIVE SILVER HALIDE EMULSION EXHIBITING A HIGH SENSITIVITY, A LOW FOG AND REDUCED VARIATION IN SENSITIVITY FOLLOWING STORAGE KONICA CORPORATION (JP) 2004-01-13 US disclosed
US-20030186180-A1 Water-based coating composition, infrared absorbing film, and photothermographic material by use thereof KONICA CORPORATION (JP) 2003-10-02 US disclosed
US-20030143499-A1 Sensitizing dye and silver halide photographic material KAGAWA NOBUAKI (JP) 2003-07-31 US disclosed
US-6489091-B2 PHOTOSENSITIVE LAYER CONTAINING ORGANIC SILVER SALT, SILVER HALIDE EMULSION AND SOLVENT ON SUPPORT KONICA CORPORATION (JP) 2002-12-03 US disclosed
US-6458519-B1 SUPPORT, SILVER HALIDE, ORGANIC SILVER SALT AND REDUCING AGENT; ANTIFOGGING, STABILITY KONICA CORPORATION (JP) 2002-10-01 US disclosed
US-4211839-A SILVER HALIDE AND ORGANIC SILVER SALT PREPARED IN AN IMINO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-07-08 US disclosed
US-4207112-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1980-06-10 US disclosed
US-4188226-A OXIDIZER, REDUCER, HALOGENATED CARBOCYCLIC COMPOUND ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-02-12 US disclosed
US-4156611-A ORGANIC SILVER SALT, SILVER HALIDE OR SILVER HALIDE FORMING COMPOUND, REDUCING AGENT, SENSITIZER FUJI PHOTO FILM CO., LTD. (JP) 1979-05-29 US disclosed
US-4128428-A ORGANIC SILVER SALT, N-HALO COMPOUND, REDUCING AGENT, IRON COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1978-12-05 US disclosed
US-4113496-A ORGANIC SILVER SALT OXIDIZING AGENT, REDUCING AGENT, HALOGEN COMPO ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1978-09-12 US disclosed
US-4106409-A Electrostatic printing method CANON KABUSHIKI KAISHA (JP) 1978-08-15 US disclosed
US-4102312-A Thermally developable light-sensitive materials TOYOTA JIDOSHA KOGYO KABUSHIKI KAISHA (JP) 1978-07-25 US disclosed
US-4030931-A PHOTOGRAPHY, SILVER HALIDES FUJI PHOTO FILM CO., LTD. (JA) 1977-06-21 US disclosed
US-4021249-A PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JA) 1977-05-03 US disclosed