SCHEMBL5167623

SCHEMBL5167623

O=c1c2ccccc2cnn1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.56
RAB9A P51151 8/20 0.56
SMN1; SMN2 Q16637 6/20 0.56
LMNA P02545 2/20 0.56
ALDH1A1 P00352 5/20 0.51
KMT2A Q03164 2/20 0.51
MEN1 O00255 1/20 0.51
GLA P06280 1/20 0.51
NFKB1 P19838 1/20 0.51
NFKB2 Q00653 1/20 0.51
RELA Q04206 1/20 0.51
POLB P06746 1/20 0.51
KDM4E B2RXH2 3/20 0.49
TDP1 Q9NUW8 2/20 0.48
PLA2G10 O15496 1/20 0.47
HSD17B10 Q99714 2/20 0.46
TP53 P04637 1/20 0.46
PAX8 Q06710 1/20 0.46
MITF O75030 1/20 0.46
PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10622783 0.90 NPC1 (0.48) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL14125604 0.80 NPC1 (0.51) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL10863971 0.79 NPC1 (0.45) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL11012126 0.76 NPC1 (0.51) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL332668 0.76 NPC1 (0.51) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL5166784 0.76 NPC1 (0.56) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL29509350 0.76 NPC1 (0.51) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL17977061 0.76 NPC1 (0.51) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL7764110 0.76 NPC1 (0.51) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL29774954 0.76 NPC1 (0.51) NPC1RAB9ASMN1; SMN2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4212937-A NITROGEN-CONTAINING HETEROCYCLIC BASE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-07-15 US claimed
CN-109843874-B Phthalazine derivatives useful as inhibitors of PARP1, PARP2 and/or tubulin for the treatment of cancer 加利福尼亚大学董事会 2022-05-27 CN disclosed
EP-1099977-B1 Preparation method of photothermographic material KONICA CORP (JP) 2007-04-11 EP disclosed
EP-1035430-B1 Silver halide photographic material KONISHIROKU PHOTO IND (JP) 2005-01-05 EP disclosed
US-6828086-B2 For use in imaging material KONICA CORPORATION (JP) 2004-12-07 US disclosed
EP-1033618-B1 Thermally developable photosensitive material KONISHIROKU PHOTO IND (JP) 2004-11-03 EP disclosed
US-6677113-B2 INFRARED-SENSITIVE SILVER HALIDE EMULSION EXHIBITING A HIGH SENSITIVITY, A LOW FOG AND REDUCED VARIATION IN SENSITIVITY FOLLOWING STORAGE KONICA CORPORATION (JP) 2004-01-13 US disclosed
US-20030186180-A1 Water-based coating composition, infrared absorbing film, and photothermographic material by use thereof KONICA CORPORATION (JP) 2003-10-02 US disclosed
US-20030143499-A1 Sensitizing dye and silver halide photographic material KAGAWA NOBUAKI (JP) 2003-07-31 US disclosed
US-6489091-B2 PHOTOSENSITIVE LAYER CONTAINING ORGANIC SILVER SALT, SILVER HALIDE EMULSION AND SOLVENT ON SUPPORT KONICA CORPORATION (JP) 2002-12-03 US disclosed
US-4770981-A MULTILAYER, DIFFUSION TRANSFER MATERIAL HAVING SPECIFIC BINDER CONCENTRATION; ANTIFOGGING AGENTS; COLOR SEPARATION; PHOTOTHERMOGRAPHY; DRY TREATMENT KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-09-13 US disclosed
EP-0190054-A2 Heat-processable color photosensitive material KONICA CORPORATION (JP) 1986-08-06 EP disclosed
US-4584267-A SILVER HALIDE, SILVER SALT, REDUCING AGENT, AND BINDER OF GELATIN OR DERIVATIVE AND POLYVINYL ALCOHOL KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-04-22 US disclosed
US-4543309-A BENZOTRIAZOLE SILVER SALT, REDUCING AGENT, BINDER, AMINO-MERCAPTO TRIAZOLE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-09-24 US disclosed
US-4539579-A ELECTROCHROMIC RECORDING THE HILTON-DAVIS CHEMICAL CO. (US) 1985-09-03 US disclosed
EP-0144087-A2 Heat-developable color light-sensitive material KONICA CORPORATION (JP) 1985-06-12 EP disclosed
EP-0136142-A2 Thermally developable, light-sensitive material KONICA CORPORATION (JP) 1985-04-03 EP disclosed
US-4451561-A Heat-development-type image recording material KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-05-29 US disclosed
US-4347310-A INCREASED PHOTOSENZITIVITY USING GUANIDINE DERIVTIVES AS SENSITIZERS; PHOTOSTABILITY; STORAGE STABILITY ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-08-31 US disclosed
US-4212937-A NITROGEN-CONTAINING HETEROCYCLIC BASE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-07-15 US disclosed