Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.38 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 2/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | ARG1 | P05089 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CPN1 | P15169 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5166901 | 1.00 | CA2 (0.41) | CA2CA12CA1CA9PTGS1 | |
| SCHEMBL22248848 | 0.82 | CA2 (0.42) | CA2CA12CA1CA9CHKA | |
| SCHEMBL14850861 | 0.82 | CA2 (0.42) | CA2CA12CA1CA9CHKA | |
| SCHEMBL20386751 | 0.82 | CA2 (0.42) | CA2CA12CA1CA9CHKA | |
| SCHEMBL6465790 | 0.82 | CA2 (0.42) | CA2CA12CA1CA9CHKA | |
| SCHEMBL10842135 | 0.82 | CA2 (0.42) | CA2CA12CA1CA9CHKA | |
| SCHEMBL22546710 | 0.80 | DPP7 (0.44) | PTGS1SLC7A11DPP4DPP7 | |
| SCHEMBL23514547 | 0.79 | CA2 (0.39) | CA2CA12CA1CA9CHKA | |
| SCHEMBL6820644 | 0.79 | DPP7 (0.56) | CA2CA12CA1CA9CHKA | |
| SCHEMBL23514439 | 0.79 | CA2 (0.39) | CA2CA12CA1CA9CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771168-A1 | COMPOSITIONS CAPABLE OF INHIBITING REACTIVE OXYGEN AND CARBONYL SPECIES | BAXTER INTERNATIONAL INC. (US) | 2007-04-11 | — | — | EP | claimed |
| WO-2006019855-A1 | COMPOSITIONS CAPABLE OF INHIBITING REACTIVE OXYGEN AND CARBONYL SPECIES | BAXTER INTERNATIONAL INC. (US) | 2006-02-23 | — | — | WO | claimed |