Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | GGT1 | P19440 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.31 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
| ▸ | PGD | P52209 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532147 | 0.80 | TSHR (0.42) | TSHRALDH1A1MEN1CYP1A2KMT2A | |
| SCHEMBL5051493 | 0.78 | TSHR (0.46) | TSHRALDH1A1MEN1CYP1A2KMT2A | |
| SCHEMBL587731 | 0.78 | TSHR (0.46) | TSHRALDH1A1MEN1CYP1A2KMT2A | |
| Bicarbonate SCHEMBL28519873 | 0.78 | TSHR (0.46) | TSHRALDH1A1MEN1CYP1A2KMT2A | |
| SCHEMBL1705101 | 0.77 | TSHR (0.43) | TSHRALDH1A1TET2CPT2ACLY | |
| SCHEMBL2784984 | 0.77 | TSHR (0.43) | TSHRALDH1A1TET2CPT2ACLY | |
| SCHEMBL28858312 | 0.77 | OR51E2 (0.38) | TSHRALDH1A1SLC1A1CPT2ACLY | |
| Bicarbonate SCHEMBL28516525 | 0.76 | TSHR (0.39) | TSHRALDH1A1MEN1CYP1A2KMT2A | |
| SCHEMBL446452 | 0.75 | TSHR (0.48) | TSHRALDH1A1TET2CPT2ACLY | |
| SCHEMBL9829180 | 0.75 | CYP1A2 (0.40) | TSHRALDH1A1MEN1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768994-A2 | CYCLIC PEPTIDE ANTIBIOTICS | Hagelin, Gunnar (NO) | 2007-04-04 | — | — | EP | claimed |
| WO-2005115097-A2 | CYCLIC PEPTIDE ANTIBIOTICS | HAGELIN GUNNAR (NO) | 2005-12-08 | — | — | WO | claimed |
| EP-1768994-A2 | CYCLIC PEPTIDE ANTIBIOTICS | Hagelin, Gunnar (NO) | 2007-04-04 | — | — | EP | disclosed |
| WO-2005115097-A2 | CYCLIC PEPTIDE ANTIBIOTICS | HAGELIN GUNNAR (NO) | 2005-12-08 | — | — | WO | disclosed |