Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Isopropyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Alcohol SCHEMBL156522 | 1.00 | — | — | |
| Isopropyl Alcohol SCHEMBL28198950 | 1.00 | TSHR (0.60) | TSHRALDH1A1LMNATDP1HSD17B10 | |
| Isopropyl Alcohol SCHEMBL3277962 | 1.00 | TSHR (0.60) | TSHRALDH1A1LMNATDP1HSD17B10 | |
| Isopropyl Alcohol SCHEMBL9460837 | 1.00 | TSHR (0.60) | TSHRALDH1A1LMNATDP1HSD17B10 | |
| Isopropyl Alcohol SCHEMBL16457736 | 1.00 | TSHR (0.60) | TSHRALDH1A1LMNATDP1HSD17B10 | |
| Isopropyl Alcohol SCHEMBL10592460 | 0.95 | TSHR (0.55) | TSHRALDH1A1LMNATDP1HSD17B10 | |
| Isopropyl Alcohol SCHEMBL17180 | 0.95 | — | — | |
| Isopropyl Alcohol SCHEMBL7541277 | 0.95 | TSHR (0.55) | TSHRALDH1A1LMNATDP1HSD17B10 | |
| Isopropyl Alcohol SCHEMBL21810764 | 0.95 | — | — | |
| Isopropyl Alcohol SCHEMBL11508242 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771507-A2 | STABILISER SYSTEM FOR HALOGENATED POLYMERS | Artemis Research GmbH & Co.KG (DE) | 2007-04-11 | — | — | EP | claimed |
| WO-2006013040-A2 | STABILISER SYSTEM FOR HALOGENATED POLYMERS | ARTEMIS RESEARCH GMBH & CO. KG (DE) | 2006-02-09 | — | — | WO | claimed |
| CN-107365275-B | High purity celecoxib | 杭州华东医药集团新药研究院有限公司 | 2020-07-03 | — | — | CN | disclosed |
| CN-107365275-A | The Sai Lexipa of high-purity | 杭州华东医药集团新药研究院有限公司 | 2017-11-21 | — | — | CN | disclosed |
| EP-1289656-A1 | REJUVENATION AND/OR CLEANING OF CATALYSTS | COLLINS, Hugh Frederick (GB) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001094013-A1 | REJUVENATION AND/OR CLEANING OF CATALYSTS | COLLINS HUGH FREDERICK (GB) | 2001-12-13 | — | — | WO | disclosed |
| US-6025502-A | CATALYTICALLY REACTING AN ARYL HYDRAZONE SUBSTITUTED ACETATE ESTER WITH A NITROGEN HETEROCYCLIC COMPOUND WHICH HAS THE NITROGEN PROTECTED, THEN DEPROTECTING | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2000-02-15 | — | — | US | disclosed |