Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Isopropyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Alcohol SCHEMBL11508242 | 1.00 | — | — | |
| Isopropyl Alcohol SCHEMBL10789711 | 1.00 | TSHR (0.55) | TSHRALDH1A1LMNATDP1HSD17B10 | |
| Isopropyl Alcohol SCHEMBL11588302 | 0.96 | TSHR (0.50) | TSHRALDH1A1LMNATDP1HSD17B10 | |
| Isopropyl Alcohol SCHEMBL9460837 | 0.95 | TSHR (0.60) | TSHRALDH1A1LMNATDP1HSD17B10 | |
| Isopropyl Alcohol SCHEMBL3277962 | 0.95 | TSHR (0.60) | TSHRALDH1A1LMNATDP1HSD17B10 | |
| Isopropyl Alcohol SCHEMBL16457736 | 0.95 | TSHR (0.60) | TSHRALDH1A1LMNATDP1HSD17B10 | |
| Isopropyl Alcohol SCHEMBL28198950 | 0.95 | TSHR (0.60) | TSHRALDH1A1LMNATDP1HSD17B10 | |
| Isopropyl Alcohol SCHEMBL5167390 | 0.95 | TSHR (0.60) | TSHRALDH1A1LMNATDP1HSD17B10 | |
| Isopropyl Alcohol SCHEMBL156522 | 0.95 | — | — | |
| Isopropyl Alcohol SCHEMBL8506612 | 0.92 | TSHR (0.46) | TSHRALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023036229-A1 | ADMIXTURE FOR CEMENT | SIKA TECHNOLOGY AG (CH) | 2023-03-16 | — | — | WO | claimed |
| WO-2023036229-A1 | ADMIXTURE FOR CEMENT | SIKA TECHNOLOGY AG (CH) | 2023-03-16 | — | — | WO | disclosed |
| EP-1005321-B1 | HAIR CONDITIONER AND 2-IN-1 CONDITIONING SHAMPOO | AKZO NOBEL NV (NL) | 2002-05-22 | — | — | EP | disclosed |
| US-6264931-B1 | REACTION PRODUCT OF ALKANOLAMINE, FATTY ACID OR FATTY ESTER AND ALKYLATION AGENT; MIXTURE WITH ANIONIC SURFACTANT | AKZO NOBEL NV. (NL) | 2001-07-24 | — | — | US | disclosed |
| US-5939059-A | Hair conditioner and 2 in 1 conditioning shampoo | AKZO NOBEL NV (NL) | 1999-08-17 | — | — | US | disclosed |