Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19897209 | 0.88 | ALDH1A1 (0.35) | RECQLALDH1A1HPGDGLAACE | |
| SCHEMBL19897343 | 0.88 | ALDH1A1 (0.35) | RECQLALDH1A1HPGDGLAACE | |
| SCHEMBL25319073 | 0.88 | ALDH1A1 (0.35) | RECQLALDH1A1HPGDGLAACE | |
| SCHEMBL25322783 | 0.88 | ALDH1A1 (0.35) | RECQLALDH1A1HPGDGLAACE | |
| SCHEMBL4678814 | 0.81 | RECQL (0.56) | RECQLALDH1A1HPGDGLAACE | |
| SCHEMBL2828543 | 0.81 | RECQL (0.56) | RECQLALDH1A1HPGDGLAACE | |
| SCHEMBL2690338 | 0.76 | CHRM2 (0.44) | RECQLALDH1A1HPGDGLAKMT2A | |
| SCHEMBL3075660 | 0.76 | CHRM2 (0.44) | RECQLALDH1A1HPGDGLAKMT2A | |
| SCHEMBL2690340 | 0.76 | CHRM2 (0.44) | RECQLALDH1A1HPGDGLAKMT2A | |
| SCHEMBL2690339 | 0.76 | CHRM2 (0.44) | RECQLALDH1A1HPGDGLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682503-B1 | DERIVATIVES OF N-[PHENYL(ALKYLPIPERIDINE-2-YL)METHYL]BENZAMIDE, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-04-11 | — | — | EP | disclosed |
| EP-1682503-A2 | DERIVATIVES OF N-[PHENYL(ALKYLPIPERIDINE-2-YL)METHYL]BENZAMIDE, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005037782-A2 | DERIVATIVES OF N-[PHENYL(ALKYLPIPERIDINE-2-YL)METHYL]BENZAMIDE, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2005-04-28 | — | — | WO | disclosed |