⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700025 | 0.79 | — | — | |
| SCHEMBL9580881 | 0.78 | — | — | |
| SCHEMBL10869219 | 0.78 | — | — | |
| SCHEMBL10409103 | 0.77 | — | — | |
| SCHEMBL1726442 | 0.77 | — | — | |
| SCHEMBL10592872 | 0.76 | LMNA (0.36) | — | |
| SCHEMBL9300886 | 0.75 | — | — | |
| SCHEMBL10270221 | 0.75 | — | — | |
| SCHEMBL9343648 | 0.71 | — | — | |
| SCHEMBL14393123 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020193649-A1 | NEW THERAPEUTIC APPLICATION OF 1,2-DIOXOLANE-3,5-DISUBSTITUTED COMPOUNDS, AND METHOD FOR THE PRODUCTION THEREOF | Universite Paris-Saclay (FR) | 2020-10-01 | — | — | WO | disclosed |
| WO-2020193650-A1 | PROCESS FOR PREPARING 1,2-ENDOPEROXIDE COMPOUNDS | Universite Paris-Saclay (FR) | 2020-10-01 | — | — | WO | disclosed |
| EP-1773784-A2 | ANTI-INFLAMMATORY MEDICAMENTS | Deciphera Pharmaceuticals, LLC (US) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006014290-A2 | ANTI-INFLAMMATORY MEDICAMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2006-02-09 | — | — | WO | disclosed |
| EP-0445751-A2 | Acid containing A-B block copolymers as grinding aids in liquid electrostatic developer preparation | DXIMAGING (US) | 1991-09-11 | — | — | EP | disclosed |