Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5171342 | 0.88 | ALDH1A1 (0.54) | KMT2AMEN1MAPTKDM4ESMARCA2 | |
| SCHEMBL5171284 | 0.79 | KDM4E (0.57) | KMT2AMEN1MAPTKDM4ELMNA | |
| SCHEMBL736708 | 0.79 | MEN1 (0.55) | KMT2AMEN1MAPTKDM4ELMNA | |
| SCHEMBL737318 | 0.78 | MEN1 (0.62) | KMT2AMEN1MAPTKDM4ELMNA | |
| SCHEMBL5172571 | 0.77 | CYP1A2 (0.59) | KMT2AMEN1MAPTKDM4ENPC1 | |
| SCHEMBL6528819 | 0.76 | CYP2D6 (0.58) | KMT2AMEN1MAPTKDM4ELMNA | |
| SCHEMBL14842148 | 0.75 | KMT2A (0.57) | KMT2AMEN1MAPTKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL31741333 | 0.75 | MAPT (0.49) | KMT2AMEN1MAPTKDM4ELMNA | |
| SCHEMBL11604511 | 0.73 | KDM4E (0.67) | KMT2AMEN1MAPTKDM4ELMNA | |
| SCHEMBL6526938 | 0.73 | CYP2C19 (0.53) | KMT2AMEN1MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007054836-A2 | 1, 2-SUBSTITUTED NAPHTHALENE DERIVATIVES WITH ANTIGLUTAMATERGIC PROPERTIES AND USES THEREOF | FAUST PHARMACEUTICALS (FR) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007054836-A2 | 1, 2-SUBSTITUTED NAPHTHALENE DERIVATIVES WITH ANTIGLUTAMATERGIC PROPERTIES AND USES THEREOF | FAUST PHARMACEUTICALS (FR) | 2007-05-18 | — | — | WO | disclosed |
| EP-1777219-A1 | 1,2-Substituted naphthalene derivatives with antiglutamatergic properties and uses thereof | Faust Pharmaceuticals (FR) | 2007-04-25 | — | — | EP | disclosed |