Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 6/20 | 0.54 |
| ▸ | HTR3A | P46098 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL516409 | 0.91 | CHRNA7 (0.46) | CHRNA7HTR3AKCNH2CHRNB4CHRNA3 | |
| SCHEMBL4035796 | 0.81 | CHRNA7 (0.56) | CHRNA7HTR3AKCNH2CHRNB4CHRNA3 | |
| SCHEMBL1689257 | 0.81 | CHRNA7 (0.68) | CHRNA7HTR3AKCNH2CHRNB4CHRNA3 | |
| SCHEMBL1688939 | 0.81 | CHRNA7 (0.61) | CHRNA7HTR3AKCNH2CHRNB4CHRNA3 | |
| SCHEMBL2638305 | 0.81 | CHRNA7 (0.65) | CHRNA7HTR3AKCNH2CHRNB4CHRNA3 | |
| SCHEMBL1753505 | 0.76 | CHRNA7 (0.78) | CHRNA7HTR3AKCNH2CHRNB4CHRNA3 | |
| SCHEMBL4035879 | 0.76 | CHRNA7 (0.55) | CHRNA7HTR3AKCNH2CHRNB4CHRNA3 | |
| SCHEMBL3649902 | 0.75 | CHRNA7 (0.54) | CHRNA7HTR3AKCNH2CHRNB4CHRNA3 | |
| SCHEMBL3646515 | 0.75 | CHRNA7 (0.57) | CHRNA7HTR3AKCNH2CHRNB4CHRNA3 | |
| SCHEMBL2638478 | 0.75 | CHRNA7 (0.60) | CHRNA7HTR3AKCNH2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028968-A1 | NOVEL DIBENZOFURANYL-OXADIAZOLYL-DIAZABICYCLONONANE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2012-02-02 | — | — | US | claimed |
| WO-2010086279-A1 | NOVEL DIBENZOFURANYL-OXADIAZOLYL-DIAZABICYCLONONANE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2010-08-05 | — | — | WO | claimed |
| US-20120028968-A1 | NOVEL DIBENZOFURANYL-OXADIAZOLYL-DIAZABICYCLONONANE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2012-02-02 | — | — | US | disclosed |
| US-20120028968-A1 | NOVEL DIBENZOFURANYL-OXADIAZOLYL-DIAZABICYCLONONANE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2012-02-02 | — | — | US | disclosed |
| US-20120028968-A1 | NOVEL DIBENZOFURANYL-OXADIAZOLYL-DIAZABICYCLONONANE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2012-02-02 | — | — | US | disclosed |
| WO-2010086279-A1 | NOVEL DIBENZOFURANYL-OXADIAZOLYL-DIAZABICYCLONONANE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010086279-A1 | NOVEL DIBENZOFURANYL-OXADIAZOLYL-DIAZABICYCLONONANE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2010-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028968-A1 | NOVEL DIBENZOFURANYL-OXADIAZOLYL-DIAZABICYCLONONANE DERIVATIVES AND THEIR MEDICAL USE | CHRNA10, CHRNA6, CHRNA7 | CHRNA7 3/4885HTR3A 259/4885KCNH2 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.