Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 1/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.49 |
| ▸ | FLT1 | P17948 | 4/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 3/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | CLK3 | P49761 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4196064 | 0.81 | CBFB (0.62) | CBFBFGFR1FLT1KDRSIRT2 | |
| SCHEMBL4184277 | 0.81 | CBFB (0.65) | CBFBFGFR1FLT1KDRCDK1 | |
| SCHEMBL4551767 | 0.80 | SIRT2 (0.56) | CBFBFGFR1FLT1SIRT2SIRT1 | |
| SCHEMBL4551786 | 0.79 | CBFB (0.56) | CBFBFGFR1FLT1KDRCDK1 | |
| SCHEMBL4143484 | 0.78 | SIRT2 (0.55) | CBFBFGFR1FLT1KDRSIRT2 | |
| SCHEMBL4139318 | 0.77 | CBFB (0.54) | CBFBFGFR1FLT1KDRCDK1 | |
| SCHEMBL4144680 | 0.76 | CBFB (0.52) | CBFBFGFR1FLT1SIRT2SIRT1 | |
| SCHEMBL15252911 | 0.76 | SIRT2 (0.50) | CBFBFGFR1FLT1KDRSIRT2 | |
| SCHEMBL15252879 | 0.74 | SIRT2 (0.50) | CBFBFGFR1FLT1KDRSIRT2 | |
| SCHEMBL4148558 | 0.73 | SIRT2 (0.53) | CBFBFGFR1FLT1KDRDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861387-A1 | NOVEL BENZOIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2007-12-05 | — | — | EP | claimed |
| WO-2006080821-A1 | NOVEL BENZOIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2006-08-03 | — | — | WO | claimed |