Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679453 | 0.86 | TP53 (1.00) | TP53TDP1NPC1CASP3SENP8 | |
| SCHEMBL15008 | 0.86 | — | — | |
| SCHEMBL29464940 | 0.86 | — | — | |
| Benzene SCHEMBL28405057 | 0.84 | TP53 (0.95) | TP53TDP1NPC1CASP3SENP8 | |
| Ethane SCHEMBL28098812 | 0.84 | TP53 (0.95) | TP53TDP1NPC1CASP3SENP8 | |
| Butadiene SCHEMBL11588880 | 0.82 | TP53 (0.91) | TP53TDP1NPC1CASP3SENP8 | |
| Styrene SCHEMBL7641096 | 0.80 | TP53 (0.87) | TP53TDP1NPC1CASP3SENP8 | |
| Methoxymethane SCHEMBL28665113 | 0.80 | TP53 (0.87) | TP53TDP1NPC1CASP3SENP8 | |
| SCHEMBL106587 | 0.79 | RAPGEF4 (0.39) | TP53TDP1ALDH1A1TSHRCYP1A2 | |
| SCHEMBL11356059 | 0.79 | RAPGEF4 (0.39) | TP53TDP1ALDH1A1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8241517-B2 | Nanostructured magnetorheological polymer fluids and gels | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) | 2012-08-14 | — | — | US | disclosed |
| US-20120025128-A1 | NANOSTRUCTURED MAGNETORHEOLOGICAL POLYMER FLUIDS AND GELS | FUCHS ALAN (US) | 2012-02-02 | — | — | US | disclosed |