Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 14/20 | 0.69 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3475210 | 1.00 | P2RX7 (0.69) | P2RX7CNR1CNR2TSHR | |
| SCHEMBL3473604 | 1.00 | P2RX7 (0.69) | P2RX7CNR1CNR2TSHR | |
| SCHEMBL3473050 | 1.00 | P2RX7 (0.69) | P2RX7CNR1CNR2TSHR | |
| SCHEMBL3472378 | 0.99 | P2RX7 (0.68) | P2RX7CNR1CNR2TSHR | |
| SCHEMBL3473729 | 0.98 | P2RX7 (0.68) | P2RX7TSHR | |
| SCHEMBL3476181 | 0.93 | P2RX7 (0.60) | P2RX7CNR1CNR2TSHR | |
| SCHEMBL3474036 | 0.92 | P2RX7 (0.59) | P2RX7CNR1CNR2 | |
| SCHEMBL3474578 | 0.92 | P2RX7 (0.58) | P2RX7CNR1CNR2 | |
| SCHEMBL3473327 | 0.92 | P2RX7 (0.67) | P2RX7CNR1CNR2 | |
| SCHEMBL3476058 | 0.91 | P2RX7 (0.57) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776352-A1 | METHOD FOR PREPARING 5-[4-(2-HYDROXY-PROPYL)-3,5-DIOXO-4,5-DIHYDRO-3H[1,2,4]TRIAZIN-2-YL]-BENZAMIDE DERIVATIVES BY DEPROTECTING THE HYDROXYL-PROTECTED PRECURSERS | Pfizer Products Inc. (US) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006003500-A1 | METHOD FOR PREPARING 5-`4-(2-HYDROXY-PROPYL)-3,5-DIOXO-4,5-DIHYDRO-3H`1,2,4!TRIAZIN-2-YL!-BENZAMIDE DERIVATIVES BY DEPROTECTING THE HYDROXYL-PROTECTED PRECURSERS | PFIZER PRODUCTS INC. (US) | 2006-01-12 | — | — | WO | disclosed |