Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 4/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | PPM1D | O15297 | 1/20 | 0.30 |
| ▸ | KLK7 | P49862 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5166076 | 0.80 | SPHK1 (0.34) | NPC1TP53HPGDTSHRRAB9A | |
| SCHEMBL7048592 | 0.77 | FFAR1 (0.31) | SLC1A3SLC1A2SLC1A1FFAR1 | |
| SCHEMBL386150 | 0.77 | POLB (0.37) | NPC1TP53HPGDTSHRRAB9A | |
| SCHEMBL386928 | 0.76 | TDP1 (0.39) | NPC1TP53HPGDTSHRRAB9A | |
| SCHEMBL5167809 | 0.75 | TDP1 (0.40) | NPC1TP53HPGDTSHRRAB9A | |
| SCHEMBL6305682 | 0.75 | SPHK1 (0.34) | — | |
| SCHEMBL5169026 | 0.73 | HPGD (0.35) | NPC1TP53HPGDTSHRRAB9A | |
| SCHEMBL385547 | 0.72 | CEL (0.39) | — | |
| SCHEMBL5166844 | 0.71 | POLB (0.34) | NPC1TP53HPGDTSHRRAB9A | |
| SCHEMBL6310394 | 0.71 | CEL (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300405-A1 | AMINO ALCOHOL DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-09 | — | — | EP | claimed |
| EP-1300405-B1 | AMINO ALCOHOL DERIVATIVES | SANKYO CO (JP) | 2007-04-18 | — | — | EP | disclosed |
| EP-1300405-A1 | AMINO ALCOHOL DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-09 | — | — | EP | disclosed |