⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23241303 | 0.67 | SMN1; SMN2 (0.39) | — | |
| Biphenyl SCHEMBL28890607 | 0.67 | ALDH1A1 (1.00) | — | |
| Biphenyl SCHEMBL1358618 | 0.67 | ALDH1A1 (1.00) | — | |
| SCHEMBL30108088 | 0.67 | ALDH1A1 (1.00) | — | |
| SCHEMBL29560186 | 0.67 | ALDH1A1 (1.00) | — | |
| Biphenyl SCHEMBL2548048 | 0.67 | ALDH1A1 (1.00) | — | |
| Biphenyl SCHEMBL4002609 | 0.67 | ALDH1A1 (1.00) | — | |
| Biphenyl SCHEMBL164 | 0.67 | ALDH1A1 (1.00) | — | |
| Biphenyl SCHEMBL29008551 | 0.67 | ALDH1A1 (1.00) | — | |
| SCHEMBL30629023 | 0.67 | ALDH1A1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020052373-A1 | Combination treatment for dementia or cognitive deficits associated with alzheimer's disease and parkinson's disease | ZORN STEVIN H (US) | 2002-05-02 | — | — | US | claimed |
| EP-1201268-A2 | Combinations of D4 dopamine receptor antagonists with acetylcholine esterase inhibitors | Pfizer Products Inc. (US) | 2002-05-02 | — | — | EP | claimed |
| EP-1343752-B1 | METHOD FOR PRODUCING N-SUBSTITUTED HYDROXYLAMINES AND THE SALTS THEREOF | SALTIGO GMBH (DE) | 2007-05-02 | — | — | EP | disclosed |
| EP-1343752-A2 | METHOD FOR PRODUCING N-SUBSTITUTED HYDROXYLAMINES AND THE SALTS THEREOF | Bayer Aktiengesellschaft (DE) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002048093-A2 | METHOD FOR PRODUCING N-SUBSTITUTED HYDROXYLAMINES AND THE SALTS THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-20 | — | — | WO | disclosed |
| US-20020052373-A1 | Combination treatment for dementia or cognitive deficits associated with alzheimer's disease and parkinson's disease | ZORN STEVIN H (US) | 2002-05-02 | — | — | US | disclosed |
| EP-1201268-A2 | Combinations of D4 dopamine receptor antagonists with acetylcholine esterase inhibitors | Pfizer Products Inc. (US) | 2002-05-02 | — | — | EP | disclosed |