Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5088782 | 0.98 | ECE2 (0.55) | SMN1; SMN2HPGDNPC1ECE2POLB | |
| Phosphoric Acid SCHEMBL5257279 | 0.93 | ECE2 (0.50) | SMN1; SMN2HPGDNPC1ECE2POLB | |
| SCHEMBL10666541 | 0.88 | SMN1; SMN2 (0.59) | SMN1; SMN2HPGDNPC1ECE2POLB | |
| SCHEMBL5094898 | 0.87 | KMT2A (0.46) | SMN1; SMN2HPGDNPC1ECE2POLB | |
| SCHEMBL10665722 | 0.86 | ECE2 (0.57) | SMN1; SMN2HPGDNPC1ECE2POLB | |
| SCHEMBL5086751 | 0.85 | MAPT (0.56) | SMN1; SMN2ECE2POLBKMT2AMEN1 | |
| SCHEMBL5247659 | 0.85 | KMT2A (0.63) | SMN1; SMN2HPGDNPC1POLBKMT2A | |
| SCHEMBL5095832 | 0.84 | ALDH1A1 (0.45) | SMN1; SMN2HPGDNPC1ECE2POLB | |
| SCHEMBL10666927 | 0.83 | ECE2 (0.54) | SMN1; SMN2HPGDNPC1ECE2POLB | |
| SCHEMBL19181001 | 0.82 | POLB (0.60) | SMN1; SMN2HPGDNPC1ECE2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099959-A1 | O-Aminophenol derivatives and colorants containing these compounds | THE PROCTER & GAMBLE COMPANY (US) | 2007-05-03 | — | — | US | claimed |
| EP-1781597-A1 | O-AMINOPHENOL DERIVATIVES AND DYES CONTAINING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-05-09 | — | — | EP | disclosed |
| US-20070099959-A1 | O-Aminophenol derivatives and colorants containing these compounds | THE PROCTER & GAMBLE COMPANY (US) | 2007-05-03 | — | — | US | disclosed |
| WO-2006021256-A1 | O-AMINOPHENOL DERIVATIVES AND DYES CONTAINING THESE COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2006-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099959-A1 | O-Aminophenol derivatives and colorants containing these compounds | KRT18, TYR, ALPG | SMN1; SMN2 4803/4885HPGD 773/4885NPC1 4823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.