Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL690466 | 0.97 | TSHR (0.35) | TSHRCYP2C19CA1CA2NT5E | |
| SCHEMBL27525935 | 0.85 | — | — | |
| SCHEMBL11288936 | 0.77 | TSHR (0.36) | TSHRCYP2C19CA1CA2 | |
| SCHEMBL3100846 | 0.77 | TSHR (0.36) | TSHRCYP2C19CA1CA2 | |
| SCHEMBL27772667 | 0.74 | TSHR (0.35) | TSHRCYP2C19CA1CA2 | |
| SCHEMBL27229156 | 0.72 | TSHR (0.33) | TSHRCYP2C19CA1 | |
| Sulfuric Acid SCHEMBL5465130 | 0.72 | TSHR (0.39) | TSHRCYP2C19CA1CA2NT5E | |
| SCHEMBL28059858 | 0.71 | GAA (0.36) | TSHRCYP2C19 | |
| SCHEMBL11452245 | 0.71 | GAA (0.36) | TSHRCYP2C19 | |
| SCHEMBL8319769 | 0.69 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118251210-A | Dissolution test | 爱尔兰詹森科学公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-118076602-A | Heteroaryl-acetylenes, pharmaceutical compositions thereof and their therapeutic uses | 嘉兴优博生物技术有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-115516044-B | Fluorescent dimer compounds useful as probes for detection of endogenous receptors | 斯特拉斯堡大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-117916215-A | Indene compound, pharmaceutical composition thereof and therapeutic application thereof | 藤济(厦门)生物医药科技有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-116848102-A | Crystalline CSF-1R inhibitor acid salt and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-116783165-A | 1,2,3, 4-tetrahydroquinoline derivatives as YAP/TAZ-TEAD activation inhibitors for the treatment of cancer | 天主教鲁汶大学 | 2023-09-19 | — | — | CN | disclosed |
| CN-116744928-A | Quinolines modulating SERCA and their use for treating diseases | 神经元公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116472034-A | Indene compound, pharmaceutical composition thereof and therapeutic application thereof | 藤济(厦门)生物医药科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-116437901-A | Treatment or prevention of diseases or conditions | 爱尔兰詹森科学公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-116437923-A | Treatment or prevention of HIV infection | 爱尔兰詹森科学公司 | 2023-07-14 | — | — | CN | disclosed |
| EP-1773916-B1 | PROCESS FOR PREPARATION OF FUNCTIONALIZED POLYIMIDES | SABIC INNOVATIVE PLASTICS IP (NL) | 2014-02-12 | — | — | EP | disclosed |
| CN-101010359-B | Process for preparation of functionalized polyimides | SABIC INNOVATIVE PLASTICS IP | 2012-07-11 | — | — | CN | disclosed |
| CN-101010359-A | Process for preparation of functionalized polyimides | GEN ELECTRIC (US) | 2007-08-01 | — | — | CN | disclosed |
| EP-1773916-A1 | PROCESS FOR PREPARATION OF FUNCTIONALIZED POLYIMIDES | The General Electric Company (US) | 2007-04-18 | — | — | EP | disclosed |
| US-7148314-B2 | Process for preparation of functionalized polyimides | GENERAL ELECTRIC COMPANY (US) | 2006-12-12 | — | — | US | disclosed |
| WO-2006014448-A1 | PROCESS FOR PREPARATION OF FUNCTIONALIZED POLYIMIDES | GENERAL ELECTRIC COMPANY (US) | 2006-02-09 | — | — | WO | disclosed |
| US-20060009613-A1 | Process for preparation of of functionalized polyimides | GENERAL ELECTRIC COMPANY | 2006-01-12 | — | — | US | disclosed |