Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.56 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25465029 | 0.77 | PTGS1 (0.57) | FABP4FABP5PTGS1PTGS2LMNA | |
| SCHEMBL28392436 | 0.76 | FABP4 (0.51) | FABP4FABP5PTGS1PTGS2LMNA | |
| SCHEMBL31156410 | 0.74 | FABP4 (0.97) | FABP4FABP5HDAC1HDAC6TBXAS1 | |
| SCHEMBL25465028 | 0.74 | PTGS1 (0.53) | FABP4FABP5PTGS1PTGS2LMNA | |
| Sebacic Acid SCHEMBL27937400 | 0.69 | TSHR (0.86) | FABP4FABP5LMNATSHRNFKB1 | |
| Sebacic Acid SCHEMBL301600 | 0.69 | TSHR (1.00) | FABP4FABP5LMNATSHRNFKB1 | |
| Adipic Acid SCHEMBL5475921 | 0.69 | TSHR (1.00) | FABP4FABP5LMNATSHRNFKB1 | |
| SCHEMBL25186232 | 0.69 | TSHR (1.00) | FABP4FABP5LMNATSHRNFKB1 | |
| SCHEMBL21065467 | 0.69 | TSHR (1.00) | FABP4FABP5LMNATSHRNFKB1 | |
| Sebacic Acid SCHEMBL20500595 | 0.69 | TSHR (1.00) | FABP4FABP5LMNATSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007107276-A3 | PROCESS FOR PREPARING C7 INTERMEDIATES AND THEIR USE IN THE PREPARATION OF N-SUBSTITUTED PYRROLE DERIVATIVES | RATIOPHARM GMBH (DE) | 2008-07-03 | — | — | WO | disclosed |
| WO-2007107276-A2 | PROCESS FOR PREPARING C7 INTERMEDIATES AND THEIR USE IN THE PREPARATION OF N-SUBSTITUTED PYRROLE DERIVATIVES | RATIOPHARM GMBH (DE) | 2007-09-27 | — | — | WO | disclosed |