SCHEMBL5170309

SCHEMBL5170309

O=C(O)O[C@@H]1CCC(=O)O1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.40
CA9 Q16790 1/20 0.40
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
CYP1A2 P05177 2/20 0.31
PRKCA P17252 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5171201 1.00 CA1 (0.40) CA1CA9LMNATSHRCYP1A2
SCHEMBL447330 1.00 CA1 (0.40) CA1CA9LMNATSHRCYP1A2
SCHEMBL10626844 0.98 CA1 (0.39) CA1CA9LMNATSHRCYP1A2
SCHEMBL6753672 0.88 CA1 (0.33) CA1CA9LMNATSHR
SCHEMBL5304809 0.82 CA1 (0.43) CA1CA9TSHRCYP1A2PRKCA
SCHEMBL9041353 0.82 CA1 (0.39) CA1CA9CYP1A2PRKCA
SCHEMBL7747592 0.82 CA1 (0.43) CA1CA9TSHRCYP1A2PRKCA
SCHEMBL5150624 0.80 CA1 (0.30) CA1CA9
Cyclohexene SCHEMBL6866890 0.79 ATM (0.32)
SCHEMBL14889302 0.77 CA1 (0.35) CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1504002-B1 METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE BETA-AMINOKETONES AND OPTICALLY ACTIVE 1,3-AMINOALCOHOLS SANOFI AVENTIS DEUTSCHLAND (DE) 2012-12-19 EP claimed
EP-1504002-A1 OPTICALLY ACTIVE &bgr;-AMINOKETONES, OPTICALLY ACTIVE 1,3-AMINOALCOHOLS AND METHOD FOR THE PRODUCTION THEREOF Aventis Pharma Deutschland GmbH (DE) 2005-02-09 EP claimed
WO-2003093259-A1 OPTICALLY ACTIVE β-AMINOKETONES, OPTICALLY ACTIVE 1,3-AMINOALCOHOLS AND METHOD FOR THE PRODUCTION THEREOF AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2003-11-13 WO claimed
EP-1504002-B1 METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE BETA-AMINOKETONES AND OPTICALLY ACTIVE 1,3-AMINOALCOHOLS SANOFI AVENTIS DEUTSCHLAND (DE) 2012-12-19 EP disclosed
EP-1299342-B1 METHOD FOR PRODUCING 3,3-DIARYLPROPYLAMINES SANOL ARZNEI SCHWARZ GMBH (DE) 2007-05-02 EP disclosed
EP-1504002-A1 OPTICALLY ACTIVE &bgr;-AMINOKETONES, OPTICALLY ACTIVE 1,3-AMINOALCOHOLS AND METHOD FOR THE PRODUCTION THEREOF Aventis Pharma Deutschland GmbH (DE) 2005-02-09 EP disclosed
WO-2003093259-A1 OPTICALLY ACTIVE β-AMINOKETONES, OPTICALLY ACTIVE 1,3-AMINOALCOHOLS AND METHOD FOR THE PRODUCTION THEREOF AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2003-11-13 WO disclosed
EP-1299342-A1 METHOD FOR PRODUCING 3,3-DIARYLPROPYLAMINES SCHWARZ PHARMA AG (DE) 2003-04-09 EP disclosed
WO-2002004399-A1 METHOD FOR PRODUCING 3,3-DIARYLPROPYLAMINES SCHWARZ PHARMA AG (DE) 2002-01-17 WO disclosed