SCHEMBL5304809

SCHEMBL5304809

CC(=O)OC1CCC(=O)O1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.43
CA9 Q16790 1/20 0.43
TSHR P16473 1/20 0.39
POLB P06746 1/20 0.34
CYP1A2 P05177 2/20 0.33
PRKCA P17252 3/20 0.33
TAS2R46 P59540 2/20 0.33
CHRM2 P08172 4/20 0.32
CHRM1 P11229 2/20 0.32
CHRM4 P08173 1/20 0.32
CHRM3 P20309 1/20 0.32
MEN1 O00255 1/20 0.32
CYP2D6 P10635 1/20 0.32
KMT2A Q03164 1/20 0.32
PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7747592 1.00 CA1 (0.43) CA1CA9TSHRPOLBCYP1A2
SCHEMBL10963251 0.87 TSHR (0.36) CA1CA9TSHRPOLBTAS2R46
SCHEMBL4093121 0.82 CA1 (0.38) CA1CA9POLBCYP1A2PRKCA
SCHEMBL75437 0.82 CA1 (0.38) CA1CA9POLBCYP1A2PRKCA
SCHEMBL5170309 0.82 CA1 (0.40) CA1CA9TSHRCYP1A2PRKCA
SCHEMBL5171201 0.82 CA1 (0.40) CA1CA9TSHRCYP1A2PRKCA
SCHEMBL447330 0.82 CA1 (0.40) CA1CA9TSHRCYP1A2PRKCA
SCHEMBL9041353 0.80 CA1 (0.39) CA1CA9CYP1A2PRKCA
SCHEMBL10626844 0.80 CA1 (0.39) CA1CA9TSHRCYP1A2PRKCA
SCHEMBL10070922 0.79 CA1 (0.39) CA1CA9CYP1A2PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110372642-B Method for treating homoserine-based compounds CJ第一制糖株式会社 2023-04-07 CN claimed
EP-3130586-B1 PROCESS FOR TREATING HOMOSERINE-BASED COMPOUND CJ CHEILJEDANG CORP (KR) 2019-10-23 EP claimed
US-10100026-B2 Process for treating homoserine-based compound CJ CHEILJEDANG CORPORATION (KR) 2018-10-16 US claimed
EP-3130586-A1 PROCESS FOR TREATING HOMOSERINE-BASED COMPOUND Cj Cheiljedang Corporation (KR) 2017-02-15 EP claimed
US-20170037019-A1 PROCESS FOR TREATING HOMOSERINE-BASED COMPOUND CJ CHEILJEDANG CORPORATION (KR) 2017-02-09 US claimed
EP-1532146-B1 A METHOD OF PREPARING ENANTIOMERS OF INDOLE-2,3-DIONE-3-OXIME DERIVATIVES NEUROSEARCH AS (DK) 2006-03-01 EP claimed
US-20050209355-A1 [Novel Reactions and the Products of Such Reactions] ROITMAN LIPA L 2005-09-22 US claimed
CN-110372642-B Method for treating homoserine-based compounds CJ第一制糖株式会社 2023-04-07 CN disclosed
EP-3130586-B1 PROCESS FOR TREATING HOMOSERINE-BASED COMPOUND CJ CHEILJEDANG CORP (KR) 2019-10-23 EP disclosed
US-10100026-B2 Process for treating homoserine-based compound CJ CHEILJEDANG CORPORATION (KR) 2018-10-16 US disclosed
US-20180120706-A1 PATTERN FORMING METHOD, LAMINATE, AND RESIST COMPOSITION FOR ORGANIC SOLVENT DEVELOPMENT FUJIFILM CORPORATION (JP) 2018-05-03 US disclosed
EP-3130586-A1 PROCESS FOR TREATING HOMOSERINE-BASED COMPOUND Cj Cheiljedang Corporation (KR) 2017-02-15 EP disclosed
US-20170037019-A1 PROCESS FOR TREATING HOMOSERINE-BASED COMPOUND CJ CHEILJEDANG CORPORATION (KR) 2017-02-09 US disclosed
WO-2007035066-A1 THE METHOD OF MAKING OPTICALLY ACTIVE 3-ACYLOXY-GAMMA-BUTYROLACTONE AND OPTICALLY ACTIVE 3-HYDROXY-GAMMA-BUTYROLACTONE BY ENZYMATIC METHOD ENZYTECH, LTD. (KR) 2007-03-29 WO disclosed
US-20050209355-A1 [Novel Reactions and the Products of Such Reactions] ROITMAN LIPA L 2005-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170037019-A1 PROCESS FOR TREATING HOMOSERINE-BASED COMPOUND CBS, CTH, DHPS CA1 4382/4885CA9 3963/4885TSHR 4048/4885
US-10100026-B2 Process for treating homoserine-based compound CBS, CTH, DHPS CA1 4382/4885CA9 3963/4885TSHR 4048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.