Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 7/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 7/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 7/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 7/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 7/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 7/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL5166797 | 0.98 | PSEN1 (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Ether SCHEMBL5166791 | 0.89 | PSEN1 (0.45) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL10280608 | 0.78 | PSEN1 (0.54) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL10435329 | 0.76 | DDB1 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7639944 | 0.74 | MAOB (0.44) | DDB1CRBNMAOBHSD11B1ALDH1A1 | |
| SCHEMBL29013938 | 0.73 | DDB1 (0.52) | DDB1CRBNMAOBHSD11B1ALDH1A1 | |
| SCHEMBL6399482 | 0.72 | PSEN1 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6399488 | 0.72 | PSEN1 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6403374 | 0.72 | PSEN1 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6403368 | 0.72 | PSEN1 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103255-B1 | METHOD OF REARING AND FEEDS | TAKARA BIO INC (JP) | 2007-05-02 | — | — | EP | disclosed |
| US-4540825-A | REARRANGEMENT OF 4-CYCLOPENTENONES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-09-10 | — | — | US | disclosed |