Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 7/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 7/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 7/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 7/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 7/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5170679 | 0.89 | PSEN1 (0.49) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Water SCHEMBL5166797 | 0.87 | PSEN1 (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL10280608 | 0.75 | PSEN1 (0.54) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Ether SCHEMBL5170417 | 0.70 | ALDH1A1 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Ether SCHEMBL5170714 | 0.70 | ALDH1A1 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6902657 | 0.68 | — | — | |
| SCHEMBL10435329 | 0.67 | DDB1 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL21821563 | 0.67 | PGR (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Ether SCHEMBL5167130 | 0.66 | PSEN1 (0.31) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7639944 | 0.66 | MAOB (0.44) | ALDH1A1DDB1CRBNKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103255-B1 | METHOD OF REARING AND FEEDS | TAKARA BIO INC (JP) | 2007-05-02 | — | — | EP | disclosed |
| EP-1000923-B1 | CYCLOPENTENONE DERIVATIVES | TAKARA BIO INC (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6552001-B1 | Method breeding and feeds | TAKARA SHUZO CO., LTD. (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-1106624-B1 | 5-MEMBERED RING COMPOUNDS | TAKARA BIO INC (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-6380262-B1 | HAVING CARCINOSTATIC ACTIVITY WHICH IS USEFUL IN A FIELD OF MEDICINE | TAKARA SHUZO CO., LTD. (JP) | 2002-04-30 | — | — | US | disclosed |
| EP-1170007-A1 | REMEDIES | Takara Shuzo Co, Ltd. (JP) | 2002-01-09 | — | — | EP | disclosed |
| EP-1106624-A1 | 5-MEMBERED RING COMPOUNDS | Takara Shuzo Co, Ltd. (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-1103255-A1 | METHOD OF REARING AND FEEDS | Takara Shuzo Co, Ltd. (JP) | 2001-05-30 | — | — | EP | disclosed |
| US-6111145-A | MONO- OR DIETHER OF 4,5-DIHYDROXY-2-CYCLOPENTEN-1-ONE OF GIVEN FORMULA, SUCH AS 4,5-DI-TERTBUTYLCYCLOPENTENONE ETHER; MADE BY REACTING THE ABOVE MENTIONED DIOL WITH ALCOHOL(S); ANTICANCER AGENT | TAKARA SHUZO COMPANY (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-1000923-A1 | CYCLOPENTENONE DERIVATIVES | Takara Shuzo Co, Ltd. (JP) | 2000-05-17 | — | — | EP | disclosed |