Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14655908 | 0.82 | AOC3 (0.34) | MTNR1AAOC3LMNATSHR | |
| SCHEMBL1535936 | 0.77 | MTNR1A (0.32) | MTNR1AAOC3LMNA | |
| SCHEMBL10354177 | 0.77 | MTNR1A (0.32) | MTNR1AAOC3LMNA | |
| SCHEMBL10358568 | 0.75 | PLK1 (0.33) | LMNATSHR | |
| SCHEMBL1887776 | 0.75 | PLK1 (0.33) | LMNATSHR | |
| SCHEMBL9101239 | 0.72 | MTNR1A (0.33) | MTNR1AAOC3LMNATSHR | |
| SCHEMBL21218965 | 0.72 | PLK1 (0.32) | LMNA | |
| SCHEMBL10354160 | 0.72 | PLK1 (0.31) | — | |
| SCHEMBL19380526 | 0.71 | KDM4E (0.49) | MTNR1ALMNA | |
| SCHEMBL27797508 | 0.71 | HSD17B10 (0.36) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1744619-A4 | MUTANT RECEPTORS AND THEIR USE IN A NUCLEAR RECEPTOR-BASED INDUCIBLE GENE EXPRESSION SYSTEM | INTREXON CORP (US) | 2007-09-26 | — | — | EP | disclosed |
| EP-1744619-A2 | MUTANT RECEPTORS AND THEIR USE IN A NUCLEAR RECEPTOR-BASED INDUCIBLE GENE EXPRESSION SYSTEM | RheoGene, Inc. (US) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005108617-A2 | MUTANT RECEPTORS AND THEIR USE IN A NUCLEAR RECEPTOR-BASED INDUCIBLE GENE EXPRESSION SYSTEM | RHEOGENE,INC. (US) | 2005-11-17 | — | — | WO | disclosed |