Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5171551 | 0.89 | TACR3 (0.70) | TACR3CYP3A4 | |
| SCHEMBL4906015 | 0.87 | TACR3 (0.79) | TACR3CYP3A4 | |
| SCHEMBL5173467 | 0.82 | TACR3 (0.60) | TACR3CYP3A4 | |
| SCHEMBL5171056 | 0.81 | TACR3 (0.75) | TACR3CYP3A4 | |
| SCHEMBL2461670 | 0.80 | DHODH (0.57) | TACR3CYP3A4 | |
| SCHEMBL5170216 | 0.79 | TACR3 (0.59) | TACR3CYP3A4 | |
| SCHEMBL5171067 | 0.77 | TACR3 (0.63) | TACR3CYP3A4 | |
| SCHEMBL5172339 | 0.76 | TACR3 (0.55) | TACR3CYP3A4 | |
| SCHEMBL5169887 | 0.76 | TACR3 (0.74) | TACR3CYP3A4 | |
| SCHEMBL4905831 | 0.76 | TACR3 (0.83) | TACR3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776344-A2 | QUINOLINE DERIVATIVES AS NEUROKININ RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME LTD. (GB) | 2007-04-25 | — | — | EP | claimed |
| WO-2006013393-A2 | QUINOLINE DERIVATIVES AS NEUROKININ RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 2006-02-09 | — | — | WO | claimed |