Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.57 |
| ▸ | ACACB | O00763 | 1/20 | 0.55 |
| ▸ | ACACA | Q13085 | 1/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10871604 | 0.98 | ACLY (0.61) | ACLYACACBACACATBXAS1PPARA | |
| SCHEMBL9131338 | 0.98 | ACLY (0.61) | ACLYACACBACACATBXAS1PPARA | |
| SCHEMBL10873588 | 0.98 | ACLY (0.61) | ACLYACACBACACATBXAS1PPARA | |
| SCHEMBL8987137 | 0.98 | ACLY (0.61) | ACLYACACBACACATBXAS1PPARA | |
| SCHEMBL2273062 | 0.93 | ACLY (0.54) | ACLYACACBACACATBXAS1PPARA | |
| SCHEMBL7222208 | 0.87 | ACLY (0.70) | ACLYACACBACACATBXAS1PPARA | |
| SCHEMBL4190226 | 0.85 | ACLY (0.74) | ACLYACACBACACATBXAS1PPARA | |
| SCHEMBL20474799 | 0.85 | ACLY (0.74) | ACLYACACBACACATBXAS1PPARA | |
| SCHEMBL1836313 | 0.85 | ACLY (0.74) | ACLYACACBACACATBXAS1PPARA | |
| SCHEMBL5528331 | 0.85 | ACLY (0.74) | ACLYACACBACACATBXAS1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049979-A2 | NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME | SENDA BIOSCIENCES, INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| CN-116836141-A | New bevacizidine intermediate, preparation method thereof and method for synthesizing bevacizidine by using same | 上海绿智创领医药科技有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-116410086-A | Method for preparing isobutyric acid derivative | 苏州特瑞药业股份有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-113372221-B | Synthesis method of 8-hydroxy-2, 14, 14-tetramethyl pentadecane diacid | 北京富盛嘉华医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| US-8642592-B2 | Oxo-heterocyclically substituted alkyl carboxylic acids and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-04 | — | — | US | disclosed |
| US-8614081-B2 | Nitrilase biocatalysts | CODEXIS, INC. (US) | 2013-12-24 | — | — | US | disclosed |
| US-20120142063-A1 | NITRILASE BIOCATALYSTS | Codexis ,Inc. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120142063-A1 | NITRILASE BIOCATALYSTS | Codexis ,Inc. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120142063-A1 | NITRILASE BIOCATALYSTS | Codexis ,Inc. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120028971-A1 | OXO-HETEROCYCLICALLY SUBSTITUTED ALKYL CARBOXYLIC ACIDS AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-02-02 | — | — | US | disclosed |
| EP-1204626-A1 | ETHER COMPOUNDS, COMPOSITIONS, AND USES THEREOF | Esperion Therapeutics Inc. (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2000059855-A1 | ETHER COMPOUNDS, COMPOSITIONS, AND USES THEREOF | ESPERION THERAPEUTICS, INC. (US) | 2000-10-12 | — | — | WO | disclosed |
| EP-0955296-A2 | Tertiary alkyl functionalized piperazine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-10 | — | — | EP | disclosed |
| EP-0111997-B1 | VINYL CARBOXYLIC ACID DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1991-04-10 | — | — | EP | disclosed |
| US-4988814-A | Antidepressants and/or anxiolytic agents | AMERICAN HOME PRODUCTS CORP. (US) | 1991-01-29 | — | — | US | disclosed |
| EP-0395313-A2 | Tertiary alkyl functionalized piperazine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-10-31 | — | — | EP | disclosed |
| US-4962106-A | Treating platelet activating factor mediated disorders | G. D. SEARLE & CO. (US) | 1990-10-09 | — | — | US | disclosed |
| EP-0186083-A2 | N-(2-Hyxdroxyalkyl)-amino acids and their derivatives, process for their preparation and pharmaceutical compositions containing them | ASTA Pharma AG (DE) | 1986-07-02 | — | — | EP | disclosed |
| US-4518602-A | Vinyl carboxylic acid derivatives, their production and use as inhibitors of thromboxane synthetase | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-05-21 | — | — | US | disclosed |
| EP-0111997-A2 | Vinyl carboxylic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028971-A1 | OXO-HETEROCYCLICALLY SUBSTITUTED ALKYL CARBOXYLIC ACIDS AND USE THEREOF | AADAC, OTC, HCAR2 | ACLY 529/4885ACACB 48/4885ACACA 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.