SCHEMBL517342

SCHEMBL517342

O=C(O)c1ccc2ccc(C(=O)O)c(C(=O)N(C3CCCCC3)C3CCCCC3)c2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
RECQL P46063 1/20 0.44
ADAM17 P78536 1/20 0.44
SLC6A4 P31645 3/20 0.41
SLC6A2 P23975 2/20 0.41
SLC6A3 Q01959 2/20 0.41
NPSR1 Q6W5P4 2/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
HSD11B1 P28845 3/20 0.39
PLA2G2D Q9UNK4 1/20 0.39
S1PR1 P21453 2/20 0.38
S1PR3 Q99500 2/20 0.38
GAA P10253 2/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL517345 0.91 PTPN1 (0.43) LMNAMEN1KMT2AKDM4EALOX15
SCHEMBL517005 0.91 PTPN1 (0.43) LMNAMEN1KMT2AKDM4EALOX15
SCHEMBL517710 0.91 PTPN1 (0.43) LMNAMEN1KMT2AKDM4EALOX15
SCHEMBL518026 0.90 PTPN1 (0.44) LMNAMEN1KMT2AKDM4EALOX15
SCHEMBL1071845 0.86 SLC6A4 (0.49) LMNAMEN1KMT2AKDM4EALOX15
SCHEMBL22471663 0.84 WDR5 (0.46) LMNAMEN1KMT2AKDM4EALOX15
SCHEMBL29539649 0.79 SLC6A4 (0.62) LMNAMEN1KMT2AKDM4EALOX15
SCHEMBL2230652 0.79 SLC6A4 (0.62) LMNAMEN1KMT2AKDM4EALOX15
SCHEMBL517351 0.79 PTPN1 (0.42) KMT2AKDM4ESLC6A4SLC6A2SLC6A3
SCHEMBL516791 0.79 PTPN1 (0.39) LMNAMEN1KMT2AKDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2392458-B1 POLYPROPYLENE RESIN MOLDED ARTICLE NEW JAPAN CHEM CO LTD (JP) 2018-03-14 EP disclosed
US-20120028006-A1 POLYPROPYLENE RESIN MOLDED ARTICLE NEW JAPAN CHEMICAL CO., LTD. (JP) 2012-02-02 US disclosed
EP-2392458-A2 POLYPROPYLENE RESIN MOLDED ARTICLE New Japan Chemical Co., Ltd. (JP) 2011-12-07 EP disclosed