Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19576374 | 0.82 | TSHR (0.56) | ALDH1A1TSHRUSP2 | |
| SCHEMBL20980007 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TSHRCYP19A1 | |
| SCHEMBL18994259 | 0.78 | CYP19A1 (0.52) | CYP19A1 | |
| SCHEMBL22926056 | 0.78 | CYP19A1 (0.52) | CYP19A1 | |
| SCHEMBL19576455 | 0.77 | CYP19A1 (0.46) | ALDH1A1TSHRUSP2CYP19A1 | |
| SCHEMBL10603561 | 0.75 | USP2 (0.36) | ALDH1A1TSHRUSP2CYP19A1 | |
| SCHEMBL10603569 | 0.75 | USP2 (0.36) | ALDH1A1TSHRUSP2CYP19A1 | |
| SCHEMBL10061275 | 0.74 | ALDH1A1 (0.40) | ALDH1A1TSHRUSP2CYP19A1 | |
| SCHEMBL5307782 | 0.73 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL10779047 | 0.73 | ALDH1A1 (0.42) | ALDH1A1TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790843-B1 | C-19-halogen-substituted steroids of the androst-9(11)-ene-series, methods for the production and use thereof | SCHERING AG (DE) | 2004-09-14 | — | — | US | claimed |
| EP-1196427-B1 | C-19-HALOGEN-SUBSTITUTED STEROIDS OF THE ANDROST-9(11)-ENE-SERIES, METHODS FOR THE PRODUCTION AND USE THEREOF | BAYER SCHERING PHARMA AG (DE) | 2007-05-23 | — | — | EP | disclosed |
| US-6790843-B1 | C-19-halogen-substituted steroids of the androst-9(11)-ene-series, methods for the production and use thereof | SCHERING AG (DE) | 2004-09-14 | — | — | US | disclosed |
| US-6790843-B1 | C-19-halogen-substituted steroids of the androst-9(11)-ene-series, methods for the production and use thereof | SCHERING AG (DE) | 2004-09-14 | — | — | US | disclosed |
| WO-2001005805-A9 | NOVEL C-19-HALOGEN-SUBSTITUTED, 5-SUBSTITUTED, 5-SUBSTITUTED OR 6,10 CARBOCYCLICALLY CONDENSED STEROIDS OF THE ANDROST-9(11)-ENE-SERIES, METHODS FOR THE PRODUCTION AND USE THEREOF | SCHERING AG (DE) | 2003-01-23 | — | — | WO | disclosed |
| WO-2001005805-A9 | NOVEL C-19-HALOGEN-SUBSTITUTED, 5-SUBSTITUTED, 5-SUBSTITUTED OR 6,10 CARBOCYCLICALLY CONDENSED STEROIDS OF THE ANDROST-9(11)-ENE-SERIES, METHODS FOR THE PRODUCTION AND USE THEREOF | SCHERING AG (DE) | 2003-01-23 | — | — | WO | disclosed |
| EP-1196427-A2 | NOVEL C-19-HALOGEN-SUBSTITUTED STEROIDS OF THE ANDROST-9(11)-ENE-SERIES, METHODS FOR THE PRODUCTION AND USE THEREOF | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-04-17 | — | — | EP | disclosed |
| EP-1196427-A2 | NOVEL C-19-HALOGEN-SUBSTITUTED STEROIDS OF THE ANDROST-9(11)-ENE-SERIES, METHODS FOR THE PRODUCTION AND USE THEREOF | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001005805-A3 | NOVEL C-19-HALOGEN-SUBSTITUTED, 5-SUBSTITUTED, 5-SUBSTITUTED OR 6,10 CARBOCYCLICALLY CONDENSED STEROIDS OF THE ANDROST-9(11)-ENE-SERIES, METHODS FOR THE PRODUCTION AND USE THEREOF | SCHERING AG (DE) | 2001-09-13 | — | — | WO | disclosed |
| WO-2001005805-A2 | NOVEL C-19-HALOGEN-SUBSTITUTED, 5-SUBSTITUTED, 5-SUBSTITUTED OR 6,10 CARBOCYCLICALLY CONDENSED STEROIDS OF THE ANDROST-9(11)-ENE-SERIES, METHODS FOR THE PRODUCTION AND USE THEREOF | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-01-25 | — | — | WO | disclosed |
| WO-2001005805-A2 | NOVEL C-19-HALOGEN-SUBSTITUTED, 5-SUBSTITUTED, 5-SUBSTITUTED OR 6,10 CARBOCYCLICALLY CONDENSED STEROIDS OF THE ANDROST-9(11)-ENE-SERIES, METHODS FOR THE PRODUCTION AND USE THEREOF | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-01-25 | — | — | WO | disclosed |