SCHEMBL517375

SCHEMBL517375

COC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.52
F2 P00734 2/20 0.39
PRSS1 P07477 2/20 0.39
PRSS2 P07478 2/20 0.39
PRSS3 P35030 2/20 0.39
CA1 P00915 10/20 0.38
CA2 P00918 10/20 0.38
ALDH1A1 P00352 1/20 0.37
GAA P10253 1/20 0.36
MMP1 P03956 2/20 0.35
MMP2 P08253 2/20 0.35
MMP9 P14780 2/20 0.35
MMP8 P22894 2/20 0.35
MMP13 P45452 2/20 0.35
DGAT1 O75907 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL517106 1.00 THRB (0.52) THRBF2PRSS1PRSS2PRSS3
SCHEMBL517316 1.00 THRB (0.52) THRBF2PRSS1PRSS2PRSS3
SCHEMBL197507 1.00 THRB (0.52) THRBF2PRSS1PRSS2PRSS3
SCHEMBL517150 1.00 THRB (0.52) THRBF2PRSS1PRSS2PRSS3
SCHEMBL674231 1.00 THRB (0.52) THRBF2PRSS1PRSS2PRSS3
SCHEMBL198030 1.00 THRB (0.52) THRBF2PRSS1PRSS2PRSS3
SCHEMBL516962 1.00 THRB (0.52) THRBF2PRSS1PRSS2PRSS3
SCHEMBL2691635 1.00 THRB (0.52) THRBF2PRSS1PRSS2PRSS3
SCHEMBL497426 1.00 THRB (0.52) THRBF2PRSS1PRSS2PRSS3
SCHEMBL196434 1.00 THRB (0.52) THRBF2PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120157105-A Method for defluorination of perfluoro and polyfluoroalkyl substances 中国科学技术大学 2025-06-17 CN claimed
CN-119503765-A Aramid nanofiber-based carbonaceous aerogel and preparation method thereof 苏州大学 2025-02-25 CN claimed
CN-119308667-A High-temperature-cured slow-release solid tracer and preparation method thereof 成都承道科技有限公司 2025-01-14 CN claimed
CN-118576785-A Super-lubricating coating with super-hydrophobic performance and preparation method thereof 四川大学华西医院 2024-09-03 CN claimed
CN-108005641-B Oil-based trace chemical tracer and method for evaluating contribution rate of oil production of each section of horizontal well 捷贝通石油技术集团股份有限公司 2023-08-15 CN claimed
CN-113653486-A Slow-release type long-acting tracer and preparation method thereof 捷贝通石油技术集团股份有限公司 2021-11-16 CN claimed
CN-108822672-B Anti-oil stain spray 天津市建筑材料科学研究院有限公司 2020-08-07 CN claimed
WO-2012024592-A2 COMPOSITIONS, METHODS, AND SYSTEMS COMPRISING FLUOROUS-SOLUBLE POLYMERS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2012-02-23 WO claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
CN-120157105-A Method for defluorination of perfluoro and polyfluoroalkyl substances 中国科学技术大学 2025-06-17 CN disclosed
CN-119683699-A Oil-soluble NiOxMethod for preparing nano particles, product and application thereof 西安浴日光能科技有限公司 2025-03-25 CN disclosed
CN-119503765-A Aramid nanofiber-based carbonaceous aerogel and preparation method thereof 苏州大学 2025-02-25 CN disclosed
CN-119308667-A High-temperature-cured slow-release solid tracer and preparation method thereof 成都承道科技有限公司 2025-01-14 CN disclosed
EP-1272336-A2 METHOD AND APPARATUS FOR MANUFACTURING PLASTIC OPTICAL TRANSMISSION MEDIUM Nanoptics, Inc. (US) 2003-01-08 EP disclosed
WO-2002066028-A2 PHARMACEUTICAL COMPOSITIONS CONTAINING FLUORINATED OR PERFLUORINATED CARBOXYLIC ACIDS CXR BIOSCIENCES LIMITED (GB) 2002-08-29 WO disclosed
US-20020041042-A1 Method and apparatus for manufacturing plastic optical transmission medium NANOPTICS, INC. 2002-04-11 US disclosed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO disclosed
WO-2001078972-A2 METHOD AND APPARATUS FOR MANUFACTURING PLASTIC OPTICAL TRANSMISSION MEDIUM NANOPTICS, INC. (US) 2001-10-25 WO disclosed